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RKTX1MAG-37K

MILLIPLEX® Rat Kidney Toxicity Panel

Configurable Rat Kidney Toxicity 7-Plex Panel

Sinónimos:

Rat renal damage panel, kidney injury biomarker panel for rats, rat drug safety kidney panel, rat nephrotoxicity multiplex assay, rat renal inflammation assay

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UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

Nombre del producto

MILLIPLEX® Rat Kidney Toxicity Panel,

Quality Segment

200

species reactivity

rat

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

inter-assay cv: <10%
intra-assay cv: <15%
(All other analytes), inter-assay cv: <20%
intra-assay cv: <30%
(GSTα), accuracy: 70-123%, standard curve range: 0.03-20 ng/mL
(IP-10, KIM-1, OPN), standard curve range: 0.03-20 ng/mL
(VEGF), standard curve range: 0.27-200 ng/mL
(TIMP-1), standard curve range: 2.06-1500 ng/mL
(Clusterin), standard curve range: 4.12-3000 ng/mL
(GSTα)

technique(s)

multiplexing: suitable

input

urine

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

KIM-1, Clusterin, and GSTα are sensitive indicators of tubular injury and cellular stress. IP-10/CXCL10 and TIMP-1 reflect renal inflammation and tissue remodeling. OPN and VEGF-A are involved in fibrosis and vascular responses. Together, these biomarkers offer a comprehensive view of kidney toxicity and repair mechanisms in rat models.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 7 analytes in rat urine samples.

Analytes Included: Clusterin, GSTα, IP-10/CXCL10, KIM-1, Osteopontin (OPN), TIMP-1, VEGF-A Note: GSTα is in a competitive assay format.

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Features:
  • Multiplex detection of 7 kidney injury biomarkers in one assay
  • Magnetic bead-based format for efficient and reproducible processing
  • Compatible with urine samples
  • High sensitivity for early detection of renal damage
Benefits:
  • Conserves sample volume and reagents through multiplexing
  • Improves data quality and reproducibility with magnetic bead format
  • Enables early detection and monitoring of kidney injury

Legal Information

Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

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pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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