Ultrafiltro Biopak®
Ultrafiltro para agua sin lipopolisacáridos bacterianos, nucleasas y bacterias en el punto de dispensación
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Referencias bibliográficas
| Visión general referencias | Pub Med ID |
|---|---|
| Polishing Up On Water Quality C. Devaux, C. Monferran, M. Tarun, E. Riche, D. Darbouret Laboratory Equipment – Chromatography Techniques (2010) Dec. 2009 Mostrar resumen Water plays a critical role in many analytical methods—particularly in the preparation of samples, standards, blanks, and eluents. It is crucial that water used for these applications does not introduce any impurities that could interfere with analytical results. As modern analytical instruments become capable of detecting ever increasingly low concentrations of analytes, ensuring the lowest level of background interference has become even more important—and more difficult. To meet this challenge, laboratory water purification systems have evolved accordingly. Current systems such as the Milli-Q Integral use a sophisticated combination of purification technologies to reduce ions, organics and other potentially background-causing contaminants to extremely low levels (i.e., 18.2 MΩ.cm resistivity and <5 µg/mL of TOC). Artículo Texto completo | |
| Endotoxin-Free Water for Tissue Culture E. Riché, J. Bôle and S. Mabic Lab Manager Magazine (2010) May 2009 Mostrar resumen Water is a ubiquitous solvent used throughout cell isolation and culture. Therefore, water contamination may affect experimental outcomes. The use of ultrapure water is advisable for culturing of cells sensitive to environmental contaminants, such as endotoxins and bacteria. Cardiomycyte isolation experiments showed that using water contaminated with bacteria and endotoxins decreases cell viability, while using freshly produced ultrapure water dramatically increases it. Additionally, an ultrafiltration cartridge will efficiently remove large molecules that may be present in water. Artículo Texto completo | |
| Water quality in patient testing J. Long and S. Mabic Clinical Lab Products (2007) April, 22-23 2007 Mostrar resumen Sophisticated diagnostic equipment is designed to improve quality, increase throughput, and manage continued labor shortages. All diagnostic manufacturers can provide the end user with software specifications that simplify automatic sampling and predilution; ensure workflow efficiency with high-speed throughput and performance; provide accuracy in testing with precision optical systems; deliver real-time access and alerts for patient and QC packages; and offer mechanical alerts to any possible instrumentation failures. Additionally, troubleshooting instrumentation, even with the above solution, creates unique challenges for medical technologists. Instrumentation can alert, flag, and warn that something is problematic, but it takes an experienced medical technologist to determine the root cause. One parameter, even though utilized by each end user on any kind of diagnostic instrument, has not been considered: water. Used in a variety of assays, water is a major reagent in clinical chemistry and immunoassay testing. Analytical factors linked to water quality need to be controlled and optimized to reduce the number of test failures. The water quality delivered to the analyzer is as important as any other reagent. Control of bacteria and its by-products with Elix technology and Biopak filters provides the highest quality water to be used in assays sensitive to these contaminants. Control of the water quality eliminates frequent decontamination. This optimizes analyzer performance and reduces downtime that can be costly to the customer and analyzer manufacturer. | Water quality in patient testing
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| Increased Flexibility in the Delivery of Ultrapure Water S. Mabic, D. Darbouret and J.F. Pilette Nature Methods (2006) 3 v-vi 2005 Mostrar resumen The Milli-Q Advantage system offers flexibility in the quality and delivery of various ultrapure water grades in laboratories. A single purification unit can be connected to up to three point-of-use dispensers, which can be equipped with different purifiers to provide the necessary water quality for various applications. The management of diverse and specific needs within the laboratory has been a driving force in developing this unique water purification system. This combination of technologies provides high-quality water with low TOC and high resistivity. Finally, this breadth of point-of-use purifiers addresses emerging needs as well as those for existing applications. Artículo Texto completo | |
| Optimized POU device for the removal of RNases and endotoxins in high purity water Mabic, Stephane, Daniel Darbouret, and Ichiro Kano Ultrapure Water, March 2003: 53-59 2003 Mostrar resumen Performances of a disposable point-of-use (POU) UF device are described here, in terms of endotoxin and RNase removal. Following a brief description of technical features and data on extractables, the efficiency of the UF on endotoxin and RNase removal is illustrated with a number of typical experiments. |
Productos y aplicaciones relacionados
Productos relacionados por: Application Facete
| Dialysis and Filtration |
Productos relacionados por: Brand Facete
| BioPak® |
Categorías
| Lab Water Purification > Lab Water Purification Consumables > Application-Paks |
El filtro Biopak® está diseñado para conectarse a la salida de los sistemas de purificación de agua como, por ejemplo, los puntos de suministro (POD) de los sistemas Milli-Q®. Sus especificaciones están garantizadas durante un periodo máximo de tres meses. El ultrafiltro está compuesto por fibras huecas de polisulfona cuya estructura se ha optimizado para rechazar con eficacia determinados contaminantes, manteniendo a la a vez un elevado caudal y reduciendo al mínimo la liberación de materiales iónicos y orgánicos.
Agua libre de bacterias y sin lipopolisacáridos bacterianos
Se sabe que los pirógenos afectan de numerosas formas a los experimentos de bioquímica y de cultivos celulares. Los más frecuentes son las endotoxinas bacterianas (LPS - lipopolisacáridos). En el agua ultrapura, las subunidades de LPS se agregan para formar estructuras de elevado peso molecular que pueden eliminarse con eficacia mediante las membranas de ultrafiltración. Se ha validado en experimentos que el filtro Biopak® puede utilizarse durante un mínimo de 90 días* para purificar el agua ultrapura con el fin de obtener concentraciones de lipopolisacáridos inferiores a 0,001 UE/ml.
Agua sin nucleasas
Los biólogos moleculares requieren sistemáticamente reactivos sin nucleasas, ya que las moléculas de ácidos nucleicos constituyen el núcleo de su investigación experimental. Se ha demostrado la ultrafiltración Biopak® como una solución práctica y eficaz para esos científicos. Y, al contrario que el DEPC (dietilpirocarbonato), la ultrafiltración no genera condiciones de manipulación peligrosas, tiempo de tratamiento prolongado o contaminación por CO2 y etanol del agua tratada. Se ha validado la eficacia de Biopak® para eliminar RNasas [< 1 (pg/ml)] y DNasas [< 5 (pg/ml)] mediante pruebas de validación. Cada unidad Biopak® se suministra con su Certificado de calidad.
*uso continuo en condiciones de prueba apropiadas
Filtro Biopak®
| Membrana | Membrana de ultrafiltración de fibra hueca |
| Material de la carcasa | Acrilonitrilo butadieno estireno (ABS) |
| Conexión de entrada | ¼" gas (recto) |
| Conexión de salida | Tubo de 8 mm (con campana protectora) |