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106447 tri-Sodium citrate dihydrate

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
6132-04-3200-675-3C₆H₅Na₃O₇ * 2 H₂O294.10 g/molPh Eur,BP,ChP,JP,USP,ACS,E 331

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      Description
      Catalogue Number106447
      SynonymsTrisodium Citrate, Sodium Citrate, Dihydrate
      References
      Product Information
      CAS number6132-04-3
      EC number200-675-3
      GradePh Eur,BP,ChP,JP,USP,ACS,E 331
      Hill FormulaC₆H₅Na₃O₇ * 2 H₂O
      Molar Mass294.10 g/mol
      HS Code2918 15 00
      Structure formula ImageStructure formula Image
      Quality LevelMQ500
      Applications
      Biological Information
      Physicochemical Information
      Melting Point300 °C (anhydrous substance)
      pH value7.5 - 9.0 (50 g/l, H₂O, 25 °C)
      Bulk density600 kg/m3
      Solubility720 g/l
      Dimensions
      Materials Information
      Toxicological Information
      LD 50 oralLD50 Rat > 8000 mg/kg
      Safety Information according to GHS
      Storage class10 - 13 Other liquids and solids
      WGKWGK 1 slightly hazardous to water
      Disposal3
      Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      StorageStore at +2°C to +30°C.
      Packaging Information
      Transport Information
      Declaration (railroad and road) ADR, RIDKein Gefahrgut
      Declaration (transport by air) IATA-DGRNo Dangerous Good
      Declaration (transport by sea) IMDG-CodeNo Dangerous Good
      Supplemental Information
      Specifications
      Assay (perchloric acid titration, calculated on dried substance)99.0 - 100.5 %
      Assay (perchloric acid titration)≥ 99.0 %
      Identitypasses test
      Appearance of solutionpasses test
      Alkalinitypasses test
      Acidity or alkalinitypasses test
      pH-value (5 %; water)7.5 - 8.5
      pH-value (5 %; water; 25 °C)7.0 - 9.0
      Insoluble matter≤ 0.005 %
      Chloride (Cl)≤ 0.003 %
      Sulfate (SO₄)≤ 0.005 %
      As (Arsenic)≤ 0.0001 %
      Ba (Barium)≤ 0.003 %
      Ca (Calcium)≤ 0.005 %
      Fe (Iron)≤ 0.0005 %
      Hg (Mercury)≤ 0.0001 %
      NH₃ (Ammonia)≤ 0.003 %
      Pb (Lead)≤ 0.0001 %
      Calcium salts or oxalate≤ 0.005 %
      Heavy metals (ACS)≤ 0.0005 %
      Heavy metals (as Pb)≤ 0.0005 %
      Oxalate (C₂O₄)≤ 0.01 %
      Tartrate (as C₄H₄O₆)passes test
      Residual solvents (ICH Q3C)excluded by manufacturing process
      Readily carbonisable substancepasses test
      Loss on drying (180 °C)11.0 - 13.0 %
      Water11.0 - 13.0 %
      Total aerobic microbial count≤ 100 CFU/g
      Total yeast and mould count≤ 10 CFU/g
      Salmonella species (absent in 10 g)passes test
      E.coli (absent in 1 g)passes test
      Staphylococcus aureus (absent in 1 g)passes test
      Pseudomonas aeruginosa (absent in 1 g)passes test
      Bile tolerante gram negative bacteria (absent in 1g)passes test
      Candida albicans (absent in 1 g)passes test
      Endotoxins≤ 2.5 I.U./g
      DNases (Exo- and endonucleases) (not detectable)passes test
      RNases (not detectable)passes test
      Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
      Corresponds to Ph Eur,BP,ChP,JP,USP,ACS,E 331
      Conforms to the purity criteria on food additives according to the current European Commission Regulation.
      Global Trade Item Number
      Catalogue Number GTIN
      1064475000 04022536076942

      Documentation

      Material Qualification Dossier

      TitleVersion
      8.0

      Quality Management Dossier (Open Access)

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      Operational Excellence Dossier

      Title

      tri-Sodium citrate dihydrate SDS

      Title

      Safety Data Sheet (SDS) 

      tri-Sodium citrate dihydrate Certificates of Analysis

      Product Number PackagingSpecificationLot Number
      1064475000 Plastic bottlePDF Specification Document

      Certificates

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