autophagy
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189497 Sigma-AldrichAutophagy Inducer, STF-62247 - CAS 315702-99-9 - Calbiochem (Autophagy Inducer, STF-62247 - CAS 315702-99-9 - Calbiochem)
A cell-permeable autophagy inducer that selectively induces non-apoptotic cell death in VHL-deficient, but not VHL-expressing, renal carcinoma cells both in vitro and in mice in vivo.
189490 Sigma-AldrichAutophagy Inhibitor, 3-MA - CAS 5142-23-4 - Calbiochem (Autophagy Inhibitor, 3-MA - CAS 5142-23-4 - Calbiochem)
Autophagy Inhibitor, 3-MA, CAS 5142-23-4, is a cell-permeable autophagic sequestration blocker that protects cerebellar granule cells from apoptosis following serum/potassium deprivation.
573121 Sigma-AldrichSMER28 - CAS 307538-42-7 - Calbiochem (SMER28 - CAS 307538-42-7 - Calbiochem)
A cell-permeable quinazoline compound that augments the cytostatic effects of Rapamycin and acts as an autophagy stimulator both in mammalian cultures in vitro and in a Drosophila melanogaster HD model in vivo.
506416 Sigma-AldrichBeclin-1 Activator II, retro-inverso TAT-Beclin-1 - Calbiochem (Beclin-1 Activator II, retro-inverso TAT-Beclin-1 - Calbiochem)
Beclin-1 Activator II, retro-inverso TAT-Beclin-1 is a cell-permeable, all-D-amino acid autophagy-inducing peptide based on the retro-inverso sequence of Tat-Beclin1 (Cat. No. 506048).
500554 Sigma-AldrichmTOR Activator, MHY1485 - CAS 326914-06-1 - Calbiochem (mTOR Activator, MHY1485 - CAS 326914-06-1 - Calbiochem)
mTOR Activator, MHY1485, CAS Number: 326914-06-1, is a cell-permeable activator of mTOR that inhibits autophagy by suppressing the fusion between autophagosomes and lysosomes.
506048 Sigma-AldrichBeclin-1 Activator I, TAT-Beclin-1 - Calbiochem (Beclin-1 Activator I, TAT-Beclin-1 - Calbiochem)
Beclin-1 Activator I, TAT-Beclin-1, is a cell-permeable Atg6/Beclin1-derived autophagy-inducing peptide. Activates Beclin1 by competing against its negative regulator GAPR-1/GLIPR2.
ABC213 Sigma-AldrichAnti-phospho ULK1 Antibody (Ser777) (Anti-phospho ULK1 Antibody (Ser777))
Anti-phospho ULK1 Antibody (Ser777) is a highly specific rabbit polyclonal antibody, that targets Autophagy-related protein & has been tested in western blotting & Peptide Inhibition Assay.
MAB2605 Sigma-AldrichAnti-ATG5 Antibody, clone 177.19 (Anti-ATG5 Antibody, clone 177.19)
This Anti-ATG5 Antibody, clone 177.19 is validated for use in WB, IP for the detection of ATG5.
AB2953 Sigma-AldrichAnti-ATG3 Antibody (Anti-ATG3 Antibody)
Anti-ATG3 Antibody detects level of ATG3 & has been published & validated for use in WB.
509272 Sigma-AldrichHydroxychloroquine Sulfate - CAS 747-36-4 - Calbiochem (Hydroxychloroquine Sulfate - CAS 747-36-4 - Calbiochem)
A cell-permeable compound that increases intralysosomal pH and impairs autophagic degradation process. Suppresses proliferation of human dermal fibroblasts (IC₅₀ = 30 µM).