573097 Sigma-AldrichSTAT3 Inhibitor III, WP1066
STAT3 Inhibitor III, WP1066, CAS 857064-38-1, is a cell-permeable AG490 tyrphostin analog that acts as a STAT3 pathway inhibitor. A potent anti-tumor agent.
More>> STAT3 Inhibitor III, WP1066, CAS 857064-38-1, is a cell-permeable AG490 tyrphostin analog that acts as a STAT3 pathway inhibitor. A potent anti-tumor agent. Less<<STAT3 Inhibitor III, WP1066 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Recommended Products
Overview
| Replacement Information |
|---|
Key Spec Table
| CAS # | Empirical Formula |
|---|---|
| 857064-38-1 | C₁₇H₁₄BrN₃O |
Products
| Catalogue Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 573097-10MGCN | 玻璃瓶 | 10 mg |
| Description | |
|---|---|
| Overview | A cell-permeable AG 490 (Cat. No. 658401) tyrphostin analog that acts as an effective STAT3 pathway inhibitor and a much more potent antitumor agent than AG 490 in inhibiting malignant glioma growth both in cultures in vitro (IC50 = 5.6 and 3.7 µM in a viability assay using U87-MG and U373-MG, respectively; no inhibition against nontumor NHA at 10 µM) and in mice in vivo. Shown to cross blood-brain barrier in mice in vivo. Also available in InSolution™ format (Cat. No. 573129. |
| Catalogue Number | 573097 |
| Brand Family | Calbiochem® |
| References | |
|---|---|
| References | Iwamaru, A., et al. 2007. Oncogene, 26, 2435. |
| Product Information | |
|---|---|
| CAS number | 857064-38-1 |
| ATP Competitive | N |
| Form | Off-white solid |
| Hill Formula | C₁₇H₁₄BrN₃O |
| Chemical formula | C₁₇H₁₄BrN₃O |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
|---|
| Physicochemical Information | |
|---|---|
| Cell permeable | Y |
| Dimensions |
|---|
| Materials Information |
|---|
| Toxicological Information |
|---|
| Safety Information according to GHS |
|---|
| Safety Information |
|---|
| Product Usage Statements |
|---|
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
|---|
| Supplemental Information |
|---|
| Specifications |
|---|
| Global Trade Item Number | |
|---|---|
| Catalogue Number | GTIN |
| 573097-10MGCN | 04055977266382 |
Documentation
STAT3 Inhibitor III, WP1066 MSDS
| Title |
|---|
STAT3 Inhibitor III, WP1066 Certificates of Analysis
| Title | Lot Number |
|---|---|
| 573097 |
References
| Reference overview |
|---|
| Iwamaru, A., et al. 2007. Oncogene, 26, 2435. |
Brochure
| Title |
|---|
| An Introduction to Inhibitors and Their Biological Applications - 1st Edition |
| Pathways and Biomarkers of JAK/STAT Signaling |
Technical Info
| Title |
|---|
| JAK/STAT Signaling Research Focus |