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559393 SB 202190, Hydrochloride - CAS 350228-36-3 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
350228-36-3C₂₀H₁₄FN₃O · HCl

Products

Catalogue NumberPackaging Qty/Pack
559393-1MGCN 塑膠安瓿;塑膠針藥瓶 1 mg
Description
OverviewA water-soluble form of the potent p38 MAP kinase inhibitor SB 202190 (Cat. No. 559388).
Catalogue Number559393
Brand Family Calbiochem®
Synonyms4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H-imidazole, HCl, p38 MAP Kinase Inhibitor II, Hydrochloride
Product Information
CAS number350228-36-3
ATP CompetitiveY
FormAmber solid
Hill FormulaC₂₀H₁₄FN₃O · HCl
Chemical formulaC₂₀H₁₄FN₃O · HCl
Hygroscopic Hygroscopic
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary Targetp38β
Primary Target IC<sub>50</sub>350 nM against the kinase activity of p38β; 280 nM against p38 phosphorylation of activating transcription factor 2 (ATF-2)
Primary Target K<sub>i</sub>16 nM
Purity≥97% by HPLC
Physicochemical Information
Cell permeableY
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 weeks at -20°C.
Global Trade Item Number
Catalogue Number GTIN
559393-1MGCN 04055977192544