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551850 Quinacrine, Dihydrochloride - CAS 69-05-6 - Calbiochem

A non-specific phospholipase A2 (PLA2) inhibitor.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Mepacrine

Primary Target: PLA₂
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
69-05-6C₂₃H₃₀CIN₃O · 2HCl

Products

Catalogue NumberPackaging Qty/Pack
551850-100MGCN 塑膠安瓿;塑膠針藥瓶 100 mg
Description
OverviewA non-specific phospholipase A2 (PLA2) inhibitor. Acts as an acetylcholine receptor antagonist. Suppresses glibenclamide-sensitive K+-currents (IC50 = 4.4 µM). Also inhibits monoamine oxidase (MAO).
Catalogue Number551850
Brand Family Calbiochem®
SynonymsMepacrine
References
ReferencesHolscher, C. 1995. Neurobiol. Learn. Mem. 63, 206.
Sakuta, H. and Yoneda, I. 1994. Eur. J. Pharmacol. 252, 117.
Sargent, C.A., et al 1992. J. Pharmacol. Exp. Ther. 262, 1161.
Voorhis, B.J., et al. 1992. Invertebr. Reprod. Dev. 21, 33.
Murakami, M., et al. 1991. Biochem. Biophys. Res. Commun. 181, 714.
Product Information
CAS number69-05-6
ATP CompetitiveN
FormYellow solid
Hill FormulaC₂₃H₃₀CIN₃O · 2HCl
Chemical formulaC₂₃H₃₀CIN₃O · 2HCl
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetPLA₂
Primary Target IC<sub>50</sub>4.4 µM in suppressing glibenclamide-sensitive K+-currents
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSAR7875000
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 36

Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +15°C to +30°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsStock solutions are stable for up to 60 h at 20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
551850-100MGCN 04055977268287

Documentation

Quinacrine, Dihydrochloride - CAS 69-05-6 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Quinacrine, Dihydrochloride - CAS 69-05-6 - Calbiochem Certificates of Analysis

TitleLot Number
551850

References

Reference overview
Holscher, C. 1995. Neurobiol. Learn. Mem. 63, 206.
Sakuta, H. and Yoneda, I. 1994. Eur. J. Pharmacol. 252, 117.
Sargent, C.A., et al 1992. J. Pharmacol. Exp. Ther. 262, 1161.
Voorhis, B.J., et al. 1992. Invertebr. Reprod. Dev. 21, 33.
Murakami, M., et al. 1991. Biochem. Biophys. Res. Commun. 181, 714.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision16-May-2008 RFH
SynonymsMepacrine
DescriptionPhospholipase A2 (PLA2) inhibitor. Acts as an acetylcholine antagonist. Suppresses glibenclamide-sensitive K+-currents (IC50 = 4.4 µM). Also inhibits monoamide oxidase (MAO).
FormYellow solid
CAS number69-05-6
RTECSAR7875000
Chemical formulaC₂₃H₃₀CIN₃O · 2HCl
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityH₂O
Storage Protect from light
+15°C to +30°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsStock solutions are stable for up to 60 h at 20°C.
Toxicity Harmful
Merck USA index14, 8044
ReferencesHolscher, C. 1995. Neurobiol. Learn. Mem. 63, 206.
Sakuta, H. and Yoneda, I. 1994. Eur. J. Pharmacol. 252, 117.
Sargent, C.A., et al 1992. J. Pharmacol. Exp. Ther. 262, 1161.
Voorhis, B.J., et al. 1992. Invertebr. Reprod. Dev. 21, 33.
Murakami, M., et al. 1991. Biochem. Biophys. Res. Commun. 181, 714.