497985 Sigma-AldrichOrnithine Decarboxylase Inhibitor, POB - Calbiochem
The Ornithine Decarboxylase Inhibitor, POB controls the biological activity of Ornithine Decarboxylase.
More>> The Ornithine Decarboxylase Inhibitor, POB controls the biological activity of Ornithine Decarboxylase. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: N-(4ʹ-Pyridoxyl)-Ornithine(BOC)-OMe, ODC Inhibitor, POB
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Overview
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Key Spec Table
| Empirical Formula |
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| C₁₉H₃₁N₃O₆ |
Products
| Catalogue Number | Packaging | Qty/Pack | |
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| 497985-10MGCN | 玻璃瓶 | 10 mg |
| Description | |
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| Overview | A cell-permeable pyridoxyl-ornithine compound that acts as an effective analog of the transition state coenzyme-substrate adduct during orthithine decarboxylase- (ODC) catalyzed conversion of L-orthithine to Pultrescine. POB is typically 5- to 10-fold more potent than DFMO (Cat. No. 288500) in inhibiting intracellular ODC activity and tumor cell growth in cultures, while exhibiting little effect against the growth of nontumorigenic human aortic smooth muscle cells. |
| Catalogue Number | 497985 |
| Brand Family | Calbiochem® |
| Synonyms | N-(4ʹ-Pyridoxyl)-Ornithine(BOC)-OMe, ODC Inhibitor, POB |
| References | |
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| References | Wu, F., et al. 2007. Mol. Cancer Ther. 6, 1831. |
| Product Information | |
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| Form | White to off-white solid |
| Formulation | Supplied as a hydrochloride salt. |
| Hill Formula | C₁₉H₃₁N₃O₆ |
| Chemical formula | C₁₉H₃₁N₃O₆ |
| Hygroscopic | Hygroscopic |
| Structure formula Image | |
| Quality Level | MQ100 |
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| Biological Information | |
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| Purity | ≥95% by HPLC |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 497985-10MGCN | 04055977199888 |
Documentation
Ornithine Decarboxylase Inhibitor, POB - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 497985 |
References
| Reference overview |
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| Wu, F., et al. 2007. Mol. Cancer Ther. 6, 1831. |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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