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311203 NG,NG-Dimethyl-L-arginine, Dihydrochloride - CAS 220805-22-1 - Calbiochem

Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
220805-22-1C₈H₁₈N₄O₂ . 2HCl

Products

Catalogue NumberPackaging Qty/Pack
311203-25MGCN 塑膠安瓿;塑膠針藥瓶 25 mg
Description
OverviewA cell-permeable, reversible inhibitor of nitric oxide synthase in vitro (IC50 = 2-3 µM) and in vivo. Causes dose-dependent vasoconstriction and bradycardic effects.
Catalogue Number311203
Brand Family Calbiochem®
SynonymsADMA, 2HCl
References
ReferencesCloss, E.I., et al. 1997. Nitric Oxide 1, 65.
Faraci, F.M., et al. 1995. Am. J. Physiol. 269, H1522.
Gardiner, S.M., et al. 1993. Br. J. Pharmacol. 110, 1457.
Kotani, K., et al. 1992. J. Neurochem. 58, 1127.
Vallance, P., et al. 1992. Lancet 339, 572.
Product Information
CAS number220805-22-1
ATP CompetitiveN
FormWhite amorphous solid
Hill FormulaC₈H₁₈N₄O₂ . 2HCl
Chemical formulaC₈H₁₈N₄O₂ . 2HCl
Hygroscopic Hygroscopic
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetNOS in vitro
Primary Target IC<sub>50</sub>2-3 µM inhibiting nitric oxide synthase in vitro
Purity≥98% by TLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
311203-25MGCN 04055977216851

Documentation

NG,NG-Dimethyl-L-arginine, Dihydrochloride - CAS 220805-22-1 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

NG,NG-Dimethyl-L-arginine, Dihydrochloride - CAS 220805-22-1 - Calbiochem Certificates of Analysis

TitleLot Number
311203

References

Reference overview
Closs, E.I., et al. 1997. Nitric Oxide 1, 65.
Faraci, F.M., et al. 1995. Am. J. Physiol. 269, H1522.
Gardiner, S.M., et al. 1993. Br. J. Pharmacol. 110, 1457.
Kotani, K., et al. 1992. J. Neurochem. 58, 1127.
Vallance, P., et al. 1992. Lancet 339, 572.

Brochure

Title
Pathways and Biomarkers of Oxidative Stress
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision19-June-2008 RFH
SynonymsADMA, 2HCl
DescriptionEndogenous reversible inhibitor of nitric oxide synthesis in vitro and in vivo. Causes dose-dependent vasoconstriction and bradycardic effects.
FormWhite amorphous solid
Intert gas (Yes/No) Packaged under inert gas
CAS number220805-22-1
Chemical formulaC₈H₁₈N₄O₂ . 2HCl
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityH₂O (50 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
Toxicity Standard Handling
ReferencesCloss, E.I., et al. 1997. Nitric Oxide 1, 65.
Faraci, F.M., et al. 1995. Am. J. Physiol. 269, H1522.
Gardiner, S.M., et al. 1993. Br. J. Pharmacol. 110, 1457.
Kotani, K., et al. 1992. J. Neurochem. 58, 1127.
Vallance, P., et al. 1992. Lancet 339, 572.