445800 Sigma-AldrichMerbarone - CAS 97534-21-9 - Calbiochem
A cell-permeable anticancer drug that inhibits the catalytic activity of topoisomerase II (topo II) without damaging DNA or stabilizing DNA-topo II cleavable complexes.
More>> A cell-permeable anticancer drug that inhibits the catalytic activity of topoisomerase II (topo II) without damaging DNA or stabilizing DNA-topo II cleavable complexes. Less<<Merbarone - CAS 97534-21-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: 5-(N-Phenylcarboxamido)-2-thiobarbituric Acid, NSC-336628
Recommended Products
Overview
| Replacement Information |
|---|
Key Spec Table
| CAS # | Empirical Formula |
|---|---|
| 97534-21-9 | C₁₁H₉N₃O₃S |
Products
| Catalogue Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 445800-25MGCN | 塑膠安瓿;塑膠針藥瓶 | 25 mg |
| References | |
|---|---|
| References | Khelifa, T., and Beck, W.T. 1999. Mol. Pharmacol. 55, 548. Drake, F.H., et al. 1989. Cancer Res. 49, 2578. Brewer, A.D., et al. 1985. Biochem. Pharmacol. 34, 2047. |
| Product Information | |
|---|---|
| CAS number | 97534-21-9 |
| ATP Competitive | N |
| Form | Faint pink solid |
| Hill Formula | C₁₁H₉N₃O₃S |
| Chemical formula | C₁₁H₉N₃O₃S |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
|---|
| Biological Information | |
|---|---|
| Primary Target | Catalytic activity of topoisomerase II |
| Primary Target IC<sub>50</sub> | 20 µM for purified topoisomerase II (topo II) |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | Y |
| Dimensions |
|---|
| Materials Information |
|---|
| Toxicological Information |
|---|
| Safety Information according to GHS | |
|---|---|
| RTECS | UV7714625 |
| Safety Information |
|---|
| Product Usage Statements |
|---|
| Storage and Shipping Information | |
|---|---|
| Ship Code | Ambient Temperature Only |
| Toxicity | Standard Handling |
| Storage | +2°C to +8°C |
| Protect from Light | Protect from light |
| Do not freeze | Ok to freeze |
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
|---|
| Supplemental Information |
|---|
| Specifications |
|---|
| Global Trade Item Number | |
|---|---|
| Catalogue Number | GTIN |
| 445800-25MGCN | 04055977204568 |
Documentation
Merbarone - CAS 97534-21-9 - Calbiochem MSDS
| Title |
|---|
Merbarone - CAS 97534-21-9 - Calbiochem Certificates of Analysis
| Title | Lot Number |
|---|---|
| 445800 |
References
| Reference overview |
|---|
| Khelifa, T., and Beck, W.T. 1999. Mol. Pharmacol. 55, 548. Drake, F.H., et al. 1989. Cancer Res. 49, 2578. Brewer, A.D., et al. 1985. Biochem. Pharmacol. 34, 2047. |