475882 Sigma-AldrichML-9, Hydrochloride - CAS 105637-50-1 - Calbiochem
A cell-permeable, reverisible and ATP-competitive inhibitor of myosin light chain kinase (Ki = 3.8 µM), protein kinase A (Ki = 32 µM), and protein kinase C (Ki = 54 µM).
More>> A cell-permeable, reverisible and ATP-competitive inhibitor of myosin light chain kinase (Ki = 3.8 µM), protein kinase A (Ki = 32 µM), and protein kinase C (Ki = 54 µM). Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: 1-(5-Chloronaphthalene-1-sulfonyl)homopiperazine, HCl
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Overview
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Key Spec Table
| CAS # | Empirical Formula |
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| 105637-50-1 | C₁₅H₁₇ClN₂O₂S · HCl |
Products
| Catalogue Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 475882-1MGCN | 塑膠安瓿;塑膠針藥瓶 | 1 mg |
| Product Information | |
|---|---|
| CAS number | 105637-50-1 |
| ATP Competitive | Y |
| Form | White solid |
| Hill Formula | C₁₅H₁₇ClN₂O₂S · HCl |
| Chemical formula | C₁₅H₁₇ClN₂O₂S · HCl |
| Hygroscopic | Hygroscopic |
| Reversible | Y |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | Mlck |
| Primary Target K<sub>i</sub> | 3.8 µM, 32 µM, 54 µM against myosin light chain kinase, protein kinase A, and protein kinase C, respectively |
| Purity | ≥98% by TLC |
| Physicochemical Information | |
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| Cell permeable | Y |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 475882-1MGCN | 04055977203509 |
Documentation
ML-9, Hydrochloride - CAS 105637-50-1 - Calbiochem MSDS
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ML-9, Hydrochloride - CAS 105637-50-1 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 475882 |
References
| Reference overview |
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| Reig, J.A., et al. 1993. Neurochem. Res. 18, 317. Nagatsu, T., et al. 1987. Biochem. Biophys. Res. Commun. 143, 1045. Saitoh, M., et al. 1987. J. Biol. Chem. 262, 7796. Saitoh, M., et al. 1986. Biochem. Biophys. Res. Commun. 140, 280. |