Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

422686 Kininogen, High Molecular Weight, Single Chain, Human Plasma - Calbiochem

View Products on Sigmaaldrich.com
422686
Purchase on Sigma-Aldrich

Overview

Products

Catalogue NumberPackaging Qty/Pack
422686-1MGCN 塑膠安瓿;塑膠針藥瓶 1 mg
Description
OverviewNative, single chain, high molecular weight Kininogen from human plasma. Nonenzymatic cofactor of the contact activation system. Links prekallikrein to negatively charged surfaces, thereby allowing activation to kallikrein by surface-bound Factor α-XIIa. Also circulates in plasma in complex with Factor XI and may play a role in the activation of Factor XI to Factor XIa by Factor α-XIIa. Serves as a source of bradykinin, a potent vasoactive peptide important in hypotension studies.
Catalogue Number422686
Brand Family Calbiochem®
References
ReferencesWeisel, J.W., et al. 1994. J. Biol. Chem. 269, 10100.
Product Information
FormLiquid
FormulationIn 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.
Quality LevelMQ100
Biological Information
Purity≥95% by SDS-PAGE
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Concentration Label Please refer to vial label for lot-specific concentration
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Global Trade Item Number
Catalogue Number GTIN
422686-1MGCN 04055977187212