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407951 Ionomycin, Free Acid, Streptomyces conglobatus in Solution - CAS 56092-81-0 - Calbiochem

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407951
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
56092-81-0C₄₁H₇₂O₉

Products

Catalogue NumberPackaging Qty/Pack
407951-1MGCN 塑膠安瓿;塑膠針藥瓶 1 mg
Description
Catalogue Number407951
Brand Family Calbiochem®
References
ReferencesAagaard-Tillery, K.M., and Jelinek, D.F. 1995. J. Immunol. 155, 3297.
Takei, N., and Endo, Y. 1994. Brain Res. 652, 65.
Dupuy d’Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
Lee, H.C. 1993. J. Biol. Chem. 268, 293.
Kuznetsov, G., et al. 1992. J. Biol. Chem. 267, 3932.
Toeplitz, B.K., et al. 1979. J. Am. Chem. Soc. 101, 3344.
Liu, C.M., and Hermann, T.E. 1978. J. Biol. Chem. 253, 5892.
Product Information
CAS number56092-81-0
ATP CompetitiveN
FormClear, colorless to slight yellow solution
FormulationA 5 mM (1 mg/282 µl) solution of Ionomycin, Free Acid, Streptomyces conglobatus (Cat. No. 407950) in DMSO.
Hill FormulaC₄₁H₇₂O₉
Chemical formulaC₄₁H₇₂O₉
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMobile ion carrier for Ca2+.
Purity≥90% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped with Blue Ice or with Dry Ice
Toxicity Irritant
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
407951-1MGCN 04055977211580

Documentation

Ionomycin, Free Acid, Streptomyces conglobatus in Solution - CAS 56092-81-0 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Ionomycin, Free Acid, Streptomyces conglobatus in Solution - CAS 56092-81-0 - Calbiochem Certificates of Analysis

TitleLot Number
407951

References

Reference overview
Aagaard-Tillery, K.M., and Jelinek, D.F. 1995. J. Immunol. 155, 3297.
Takei, N., and Endo, Y. 1994. Brain Res. 652, 65.
Dupuy d’Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
Lee, H.C. 1993. J. Biol. Chem. 268, 293.
Kuznetsov, G., et al. 1992. J. Biol. Chem. 267, 3932.
Toeplitz, B.K., et al. 1979. J. Am. Chem. Soc. 101, 3344.
Liu, C.M., and Hermann, T.E. 1978. J. Biol. Chem. 253, 5892.

Citations

Title
  • Jonathan Rios-Doria, et al. (2004) Cleavage of b-catenin by calpain in prostate and mammary tumor cells. Cancer Research 64, 7237-7240.
    		•
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision01-April-2011 RFH
    DescriptionHighly specific for divalent cations (Ca2+ > Mg2+ >> Sr2+ = Ba2+). More effective than antibiotic A23187 as a mobile ion carrier for Ca2+. Complexes with Ca2+ between pH 7 and 9.5, causing significant absorption in the UV range; however, in contrast to A23187 (Cat. No. 100105), it is not fluorescent. Useful for studies of Ca2+ transport across biological membranes and measurement of cytoplasmic free Ca2+. Induces apoptotic neuronal degeneration in embryonic cortical neurons. Also induces cell cycle arrest in the G1 interval of mature Burkitt lymphoma cell lines.
    FormClear, colorless to slight yellow solution
    FormulationA 5 mM (1 mg/282 µl) solution of Ionomycin, Free Acid, Streptomyces conglobatus (Cat. No. 407950) in DMSO.
    Intert gas (Yes/No) Packaged under inert gas
    CAS number56092-81-0
    Chemical formulaC₄₁H₇₂O₉
    Structure formulaStructure formula
    Purity≥90% by HPLC
    Storage Protect from light
    -20°C
    Hygroscopic
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
    Toxicity Irritant
    ReferencesAagaard-Tillery, K.M., and Jelinek, D.F. 1995. J. Immunol. 155, 3297.
    Takei, N., and Endo, Y. 1994. Brain Res. 652, 65.
    Dupuy d’Angeac, A., et al. 1993. J. Cell Physiol. 154, 44.
    Lee, H.C. 1993. J. Biol. Chem. 268, 293.
    Kuznetsov, G., et al. 1992. J. Biol. Chem. 267, 3932.
    Toeplitz, B.K., et al. 1979. J. Am. Chem. Soc. 101, 3344.
    Liu, C.M., and Hermann, T.E. 1978. J. Biol. Chem. 253, 5892.
    Citation
  • Jonathan Rios-Doria, et al. (2004) Cleavage of b-catenin by calpain in prostate and mammary tumor cells. Cancer Research 64, 7237-7240.
    		•