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EZHFGF21-19K Human FGF-21 ELISA Kit

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EZHFGF21-19K
96-well strip plate  
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Overview

Replacement Information

Key Spec Table

Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
FGF-21 HELISAFluorescent Colorimetric
Description
Catalogue NumberEZHFGF21-19K
DescriptionHuman FGF-21 ELISA Kit
Background InformationRecent studies have demonstrated that fibroblast growth factor 21 (FGF-21), a liver derived protein, is able to increase glucose uptake, as well as lower plasma triglyceride levels in an insulin-independent manner. FGF-21 suppresses glucagon release, thereby increasing insulin sensitivity, and reduces the amount of insulin production required by pancreatic β-cells. Unlike insulin, which works in a rapid, hormone-like manner, FGF-21 activity requires several hours, indicating changes in gene expression. While insulin functions through GLUT4 translocation, FGF-21 has been shown to act primarily through the upregulation of adipocyte GLUT1, a transporter that allows glucose to move from the blood into cells even in the absence of insulin. In addition, no significant weight gain was observed when FGF-21 was injected into animals, and mice that had been genetically engineered to overexpress FGF-21 weighed less and had less adipose tissue than the normal controls.
References
Product Information
Detection methodFluorescent Colorimetric
HS Code3002 15 90
Precision, %
  • Intra-assay: < 6%
  • Inter-assay: < 9%
Quality LevelMQ200
Applications
ApplicationThis Human FGF-21 ELISA Kit is used to measure & quantify FGF-21 levels in Metabolism & Inflammation & Immunology research.
Key Applications
  • ELISA
Application NotesThis is a 3-hour assay requiring 50 μL of sample.
Biological Information
SpecificityNo significant cross-reactivity to the cytokines and metabolic hormones tested was observed.
Species Reactivity
  • Human
Analytes Available
  • FGF-21
Accuracy
  • 83 – 99%
Physicochemical Information
Linearity of DilutionPlease contact Technical Service for this information
Standard Curve Range
  • 31.3– 2000 pg/mL
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • For research use only. Not for use in diagnostic procedures.
Storage and Shipping Information
Packaging Information
Material Size96-well strip plate
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
EZHFGF21-19K 04053252511073