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12-555 Crosstide KK

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12-555
1 mg  
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Overview

Description
Catalogue Number12-555
Brand Family Upstate
Trade Name
  • Upstate
DescriptionCrosstide KK
Product Information
Quality LevelMQ100
Applications
ApplicationCrosstide KK primarily used in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
Entrez Gene Number
Entrez Gene SummaryThis gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene Symbol
  • SGK3
  • CISK
  • DKFZp781N0293
  • SGK2
  • SGKL
Protein TargetSGK3
Target Sub-FamilyAGC
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q96BR1 # Involved in the activation of potassium channels. Mediates cell IL-3-dependent survival signals (By similarity).
SIZE: 496 amino acids; 57108 Da
SUBCELLULAR LOCATION: Cytoplasmic vesicle (By similarity). Early endosome (By similarity). Note=Localized in vesicle-like structures and in the early endosome (By similarity).
TISSUE SPECIFICITY: Expressed in most tissues with highest levels in pancreas, kidney liver, heart and brain and lower levels in lung, placenta and skeletal muscle.
SIMILARITY: SwissProt: Q96BR1 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain. & Contains 1 PX (phox homology) domain.
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation using SGK3, active (Catalog # 14-647).
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions2 years at 4°C
Packaging Information
Material Size1 mg
Global Trade Item Number
Catalogue Number GTIN
12-555 04053252583476