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05-23-0050 Corticotropin Releasing Factor, Human and Rat - CAS 86784-80-7 - Calbiochem

An immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: CRF

Primary Target: An immunomodulatory neuropeptide
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
86784-80-7C₂₀₈H₃₄₄N₆₀O₆₃S₂

Products

Catalogue NumberPackaging Qty/Pack
05230050-1MGCN 塑膠安瓿;塑膠針藥瓶 1 mg
Description
OverviewAn immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla. Functions by reducing hyperpolarizations. Acts as a functional antagonist of inflammatory mediators.
Catalogue Number05-23-0050
Brand Family Calbiochem®
SynonymsCRF
References
ReferencesBarmack, N.H., and Errico, P. 1993. J. Neurosci. 13, 4647.
Wei, E.T., et al. 1993. Ciba Found. Symp. 172, 258.
Smith, E.M., et al. 1986. Nature 321, 881.
Udelsman, R., et al. 1986. Nature 319, 147.
Product Information
CAS number86784-80-7
ATP CompetitiveN
FormWhite to off-white lyophilized solid
FormulationSupplied as an acetate salt.
Hill FormulaC₂₀₈H₃₄₄N₆₀O₆₃S₂
Chemical formulaC₂₀₈H₃₄₄N₆₀O₆₃S₂
Hygroscopic Hygroscopic
ReversibleN
Sold on the basis of peptide contentY
Quality LevelMQ100
Applications
Biological Information
Primary TargetAn immunomodulatory neuropeptide
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Peptide ContentY
Peptide SequenceH-Ser-Glu-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Met-Glu-Ile-Ile-NH₂
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSGM7925000
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
05230050-1MGCN 04055977206890

Documentation

Corticotropin Releasing Factor, Human and Rat - CAS 86784-80-7 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Corticotropin Releasing Factor, Human and Rat - CAS 86784-80-7 - Calbiochem Certificates of Analysis

TitleLot Number
05-23-0050

References

Reference overview
Barmack, N.H., and Errico, P. 1993. J. Neurosci. 13, 4647.
Wei, E.T., et al. 1993. Ciba Found. Symp. 172, 258.
Smith, E.M., et al. 1986. Nature 321, 881.
Udelsman, R., et al. 1986. Nature 319, 147.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision02-April-2009 JSW
SynonymsCRF
DescriptionReleases ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla. Functions by reducing hyperpolarizations. Acts as a functional antagonist of inflammatory mediators.
FormWhite to off-white lyophilized solid
FormulationSupplied as an acetate salt.
CAS number86784-80-7
RTECSGM7925000
Chemical formulaC₂₀₈H₃₄₄N₆₀O₆₃S₂
Peptide SequenceH-Ser-Glu-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Met-Glu-Ile-Ile-NH₂
Purity≥97% by HPLC
Solubility5% NH₄OH (prepared with H₂O) (1 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesBarmack, N.H., and Errico, P. 1993. J. Neurosci. 13, 4647.
Wei, E.T., et al. 1993. Ciba Found. Symp. 172, 258.
Smith, E.M., et al. 1986. Nature 321, 881.
Udelsman, R., et al. 1986. Nature 319, 147.