233100 Sigma-AldrichCL-387,785 - CAS 194423-06-8 - Calbiochem
A cell-permeable and irreversible inhibitor of EGF-receptor (EGFR) kinase activity in vivo (IC₅₀ = 250-490 pM) as well as EGF-stimulated autophosphorylation of tyrosine residues in the EGFR in vivo (IC₅₀ = 5 nM).
More>> A cell-permeable and irreversible inhibitor of EGF-receptor (EGFR) kinase activity in vivo (IC₅₀ = 250-490 pM) as well as EGF-stimulated autophosphorylation of tyrosine residues in the EGFR in vivo (IC₅₀ = 5 nM). Less<<Synonyms: N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-butynamide, EKI-785
Recommended Products
Overview
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Key Spec Table
CAS # | Empirical Formula |
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194423-06-8 | C₁₈H₁₃BrN₄O |
Products
Catalogue Number | Packaging | Qty/Pack | |
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233100-1MGCN | 塑膠安瓿;塑膠針藥瓶 | 1 mg |
References | |
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References | Sweeney, W.E., et al. 2000. Kidney Int. 57, 33. Discafani, C.M., et al. 1999. Biochem. Pharmacol. 57, 917. Sweeney, W.E., et. al. 1999. Kidney Int. 56, 406. |
Product Information | |
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CAS number | 194423-06-8 |
ATP Competitive | N |
Form | Pale yellow solid |
Hill Formula | C₁₈H₁₃BrN₄O |
Chemical formula | C₁₈H₁₃BrN₄O |
Hygroscopic | Hygroscopic |
Reversible | N |
Structure formula Image | |
Quality Level | MQ100 |
Applications |
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Physicochemical Information | |
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Cell permeable | Y |
Dimensions |
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Materials Information |
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Toxicological Information |
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Safety Information according to GHS |
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Safety Information |
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Product Usage Statements |
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Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Catalogue Number | GTIN |
233100-1MGCN | 04055977217612 |
Documentation
CL-387,785 - CAS 194423-06-8 - Calbiochem MSDS
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CL-387,785 - CAS 194423-06-8 - Calbiochem Certificates of Analysis
Title | Lot Number |
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233100 |
References
Reference overview |
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Sweeney, W.E., et al. 2000. Kidney Int. 57, 33. Discafani, C.M., et al. 1999. Biochem. Pharmacol. 57, 917. Sweeney, W.E., et. al. 1999. Kidney Int. 56, 406. |