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09-814 Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25)

Detect dimethyl-Arginine using this Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25) validated for use in WB.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Chromatin Biology Gene Symbol: ASYM25, ADMA
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09-814
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, H, RWBRbSerumPolyclonal Antibody
Description
Catalogue Number09-814
DescriptionAnti-dimethyl-Arginine Antibody, asymmetric (ASYM25)
Alternate Names
  • dimethyl-arginine, asymmetric
Background InformationAsymmetrical dimethlarginine (ADMA) is an endogenous, L-arginine metabolite arising from the proteolysis of methylated arginine containing proteins and is a known inhibitor of nitric oxide synthase (NOS). In various studies, ADMA has been observed as having a regulatory role in cell motility and the actin cytoskeleton. Elevated levels of ADMA are associated with sporadic FSGS, coronary artery disease, hypertension, peripheral arterial occlusive disease, obesity, stroke, preeclampsia, and cardiovascular mortality/morbidity in patients with diabetic nephropathy.
References
Product Information
FormatSerum
Control
  • PRMT1 treated and untreated MEF cell lysates
PresentationUnpurified rabbit polyclonal containing serum with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect dimethyl-Arginine using this Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25) validated for use in WB.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-conjugated linear peptide containing asymmetric dimethyl-arginine-glycine repeats.
EpitopeUnknown
HostRabbit
SpecificityThis antibody recognizes dimethylated arginines.
Species Reactivity
  • Mouse
  • Human
  • Rat
Species Reactivity NoteDemonstrated to react with mouse. Predicted to react with human and rat based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Gene Symbol
  • ASYM25
  • ADMA
Purification MethodUnpurified
Molecular WeightMultiple. This antibody detects proteins containing asymmetrical dimethylated arginines.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in PRMT1 treated and untreated MEF cell lysates.

Western Blot Analysis: 1:1,000 dilution of this antibody detected dimethyl-Arginine on 10 µg of PRMT1 treated and untreated MEF cell lysates.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
09-814 04053252288166

Documentation

Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25) MSDS

Title

Safety Data Sheet (SDS) 

Anti-dimethyl-Arginine Antibody, asymmetric (ASYM25) Certificates of Analysis

TitleLot Number
Anti-dimethyl-Arginine, asymmetric (ASYM25) - 2384758 2384758
Anti-dimethyl-Arginine, asymmetric (ASYM25) - 2000402 2000402
Anti-dimethyl-Arginine, asymmetric (ASYM25) - 2015995 2015995
Anti-dimethyl-Arginine, asymmetric (ASYM25) - 2051964 2051964
Anti-dimethyl-Arginine, asymmetric (ASYM25) - 2202498 2202498
Anti-dimethyl-Arginine, asymmetric (ASYM25) - 2332577 2332577
Anti-dimethyl-Arginine, asymmetric (ASYM25) - 3184728 3184728
Anti-dimethyl-Arginine, asymmetric (ASYM25) - 3385826 3385826
Anti-dimethyl-Arginine, asymmetric (ASYM25) - 3930313 3930313
Anti-dimethyl-Arginine, asymmetric (ASYM25) - NG1820260 NG1820260
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References

Reference overviewApplicationPub Med ID
NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink.
Ulanovskaya, OA; Zuhl, AM; Cravatt, BF
Nature chemical biology  9  300-6  2013

Show Abstract 		Western Blotting23455543 23455543

Brochure

Title
Product Selection Guide - Antibodies, small molecule inhibitors, kits, assays and proteins for signaling research.