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ST1681 Anti-SIGIRR Mouse mAb (3H8-2G3)

This Anti-SIGIRR Mouse mAb (3H8-2G3) is validated for use in Immunoblotting for the detection of SIGIRR.

Anti-SIGIRR Mouse mAb (3H8-2G3) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Single Immunoglobulin and Toll-Interleukin 1 Receptor Domain

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ST1681
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Overview

Replacement Information

Key Spec Table

Species ReactivityHostAntibody Type
HMMonoclonal Antibody

Products

Catalogue NumberPackaging Qty/Pack
ST1681-200ULCN 200 ul
Description
OverviewRecognizes the ~32 kDa SIGIRR protein in HepG2 cells.
Catalogue NumberST1681
Brand Family Calbiochem®
SynonymsAnti-Single Immunoglobulin and Toll-Interleukin 1 Receptor Domain
References
Product Information
FormLiquid
FormulationUndiluted ascites
Positive controlHepG2 cells
PreservativeNone
Quality LevelMQ100
Applications
Key Applications Immunoblotting (Western Blotting)
Application NotesImmunoblotting (1-5 µg/ml)
Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
Biological Information
ImmunogenFull-length, recombinant, human SIGIRR (aa 1-411), expressed as a GST fusion protein
Clone3H8-2G3
HostMouse
IsotypeIgM
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Regulatory Review
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ST1681-200ULCN 04055977223880

Documentation

Anti-SIGIRR Mouse mAb (3H8-2G3) MSDS

Title

Safety Data Sheet (SDS) 

Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision10-November-2010 RFH
SynonymsAnti-Single Immunoglobulin and Toll-Interleukin 1 Receptor Domain
ApplicationImmunoblotting (1-5 µg/ml)
DescriptionMouse monoclonal antibody supplied as ascites. Recognizes the ~32 kDa SIGIRR protein.
BackgroundThe SIGIRR protein acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. It attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Its extracellular domain is known to interfere with the heterodimerization of Il1R1 and IL1RAP.
HostMouse
ImmunogenFull-length, recombinant, human SIGIRR (aa 1-411), expressed as a GST fusion protein
Clone3H8-2G3
IsotypeIgM
Specieshuman
Positive controlHepG2 cells
FormLiquid
FormulationUndiluted ascites
PreservativeNone
CommentsVariables associated with assay conditions will dictate the proper working dilution.
Storage Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Regulatory Review