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MAB1281A4 Anti-Nuclei Antibody, clone 235-1, Alexa Fluor® 488 conjugate

The anti-Nuclei, clone 235-1, Alexa Fluor 488 conjugate will recognize human cell nuclei only & is usefull in xenograph transplantation studies to study stem cell migration.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Stem Cell Research, Stem Cell Research Research Sub-Category: Pluripotent & Early Differentiation, Developmental Neuroscience, Mesenchymal Stem Cells, Neurodegenerative Diseases
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MAB1281A4
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HICCMAlexaFluor®488Monoclonal Antibody
Description
Catalogue NumberMAB1281A4
DescriptionAnti-Nuclei Antibody, clone 235-1, Alexa Fluor® 488 conjugate
Alternate Names
  • HuNu
Background InformationCell replacement techniques such as stem-cell or fetal-cell therapies show great promise for many diseases. Cross-species grafting between human and animal cells or tissues requires the identification and localization of the donor material in the host environment. Antibodies to human-specific nuclei are useful cytological and histological markers for identifying human cells in xenograft models. MAB1281 stains nuclei of all human and primate cell types giving a diffuse nuclear staining pattern. Chromosomes are negatively stained in metaphase cells. The antibody does not react with nuclei from mouse or rat.
References
Product Information
FormatAlexaFluor®488
Control
  • Human foreskin fibroblasts (SCC058)
PresentationPurified mouse monoclonal IgG1 conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15mg/ml BSA.
Quality LevelMQ100
Applications
ApplicationThe anti-Nuclei, clone 235-1, Alexa Fluor 488 conjugate will recognize human cell nuclei only & is usefull in xenograph transplantation studies to study stem cell migration.
Key Applications
  • Immunocytochemistry
Application NotesEvaluated by Immunocytochemistry in human bone marrow mesenchymal stem cells (SCR108). Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected nuclei in human bone marrow mesenchymal stem cells (SCR108). Evaluated by Immunocytochemistry in H9 human embryonic stem cells. Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected nuclei in H9 human embryonic stem cells. Evaluated by Immunocytochemistry in mouse embryonic fibroblasts. Immunocytochemistry Analysis: A 1:50 dilution of this antibody did not detect nuclei in mouse embryonic fibroblasts.
Biological Information
ImmunogenHuman nuclei
CloneClone 235-1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG1
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Purification MethodProtein G Purified
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunocytochemistry in human foreskin fibroblasts (SCC058). Immunocytochemistry Analysis: A 1:50 dilution of this antibody detected nuclei in human foreskin fibroblasts (SCC058).
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MAB1281A4 04053252819223

Documentation

Anti-Nuclei Antibody, clone 235-1, Alexa Fluor® 488 conjugate MSDS

Title

Safety Data Sheet (SDS) 

Anti-Nuclei Antibody, clone 235-1, Alexa Fluor® 488 conjugate Certificates of Analysis

TitleLot Number
Anti-Nuclei, clone 235-1, Alexa Fluor#174; 488 conjugate - 2219404 2219404
Anti-Nuclei, clone 235-1, Alexa Fluor#174; 488 conjugate - Q2070088 Q2070088
Anti-Nuclei, clone 235-1, Alexa Fluor® -2550064 2550064
Anti-Nuclei, clone 235-1, Alexa Fluor® -2569202 2569202
Anti-Nuclei, clone 235-1, Alexa Fluor® -2621119 2621119
Anti-Nuclei, clone 235-1, Alexa Fluor® -2684873 2684873
Anti-Nuclei, clone 235-1, Alexa Fluor® 488 conjugate 2816713
Anti-Nuclei, clone 235-1, Alexa Fluor® 488 conjugate - 2360025 2360025
Anti-Nuclei, clone 235-1, Alexa Fluor® 488 conjugate - 2430550 2430550
Anti-Nuclei, clone 235-1, Alexa Fluor® 488 conjugate - 2460210 2460210
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