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AB1781SP Anti-Neurotrophin 4/5 Antibody

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AB1781SP
500 µg  
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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, Mk, RELISA, WB, IHC, FUNCRbPurifiedPolyclonal Antibody
Description
Catalogue NumberAB1781SP
ReplacesAB1455P
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Neurotrophin 4/5 Antibody
Alternate Names
  • NT4/5
References
Product Information
FormatPurified
HS Code3002 15 90
PresentationPurified immunoglobulin. Lyophilized from PBS, no preservatives. Reconstitute with 500 μL of sterile distilled water (1 mg/mL).
Quality LevelMQ100
Applications
ApplicationAnti-Neurotrophin 4/5 Antibody is an antibody against Neurotrophin 4/5 for use in ELISA, WB, IH.
Key Applications
  • ELISA
  • Western Blotting
  • Immunohistochemistry
  • Affects Function
Application NotesImmunohistochemistry: 1-2 μg/mL (see suggested protocol).

Immunoblotting: 1-2 μg/mL

ELISA: 1-2 μg/mL

Inhibition of biological activity in vitro: 1-2 μg/mL.
BIOLOGICAL ACTIVITY: Neutralizes NT4, but not other neurotrophins.

In vivo animal studies: use neat

Optimal working dilutions must be determined by end user.
Biological Information
ImmunogenRecombinant human Neurotrophin 4 (NT4).
HostRabbit
SpecificityNeurotrophin 4 (NT4). By dot blot, less than 1% cross-reactivity against NGF, BDNF or NT3.
Species Reactivity
  • Human
  • Mouse
  • Monkey
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThis gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.
Gene Symbol
  • NTF5
  • NT5
  • NT-4
  • NTF4
  • Neurotrophin-4
  • NT-5
  • NT-4/5
  • NT4
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P34130 # Target-derived survival factor for peripheral sensory sympathetic neurons.
SIZE: 210 amino acids; 22427 Da
SUBCELLULAR LOCATION: Secreted.
TISSUE SPECIFICITY: Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.
SIMILARITY: SwissProt: P34130 ## Belongs to the NGF-beta family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain lyophilized material at -20 to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20 to -70°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size500 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB1781SP 04053252333958

Documentation

Anti-Neurotrophin 4/5 Antibody MSDS

Title

Safety Data Sheet (SDS) 

Anti-Neurotrophin 4/5 Antibody Certificates of Analysis

TitleLot Number
RABBIT ANTI-NEUROTROPHIN 4 (NT4) 2475024
RABBIT ANTI-NEUROTROPHIN 4 (NT4) (IgG Fraction) - 3500943 3500943
RABBIT ANTI-NEUROTROPHIN 4 (NT4) (IgG Fraction) POLYCLONAL ANTIBODY 2900222
RABBIT ANTI-NEUROTROPHIN 4 (NT4) (IgG Fraction) POLYCLONAL ANTIBODY - 2204932 2204932
RABBIT ANTI-NEUROTROPHIN 4 (NT4) (IgG Fraction) POLYCLONAL ANTIBODY - 2301264 2301264
RABBIT ANTI-NEUROTROPHIN 4 (NT4) (IgG Fraction) POLYCLONAL ANTIBODY - 2358859 2358859
RABBIT ANTI-NEUROTROPHIN 4 (NT4) - 2151856 2151856
RABBIT ANTI-NEUROTROPHIN 4 (NT4) -2550609 2550609
RABBIT ANTI-NEUROTROPHIN 4 (NT4) -2640550 2640550
RABBIT ANTI-NEUROTROPHIN 4 (NT4) -2816751 2816751