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05-683 Anti-Mps1 Antibody, CT, clone 4-112-3

Anti-Mps1 Antibody, CT, clone 4-112-3 is a high quality Mouse Monoclonal Antibody for the detection of Mps1 & has been validated in IP, WB, ICC.

Anti-Mps1 Antibody, CT, clone 4-112-3 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Cell Cycle, DNA Replication & Repair Gene Symbol: TTK, PYT, MPS1L1, ESK, FLJ38280 UniProt Number: P33981
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05-683
200 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HIP, WB, ICCMPurifiedMonoclonal Antibody
Description
Catalogue Number05-683
Brand Family Upstate
Trade Name
  • Upstate
DescriptionAnti-Mps1 Antibody, CT, clone 4-112-3
OverviewThis antibody is known to inhibit the autophos-phorylation/kinase activity of Mps1; Mps1 was previously known as TTK/PYK
References
Product Information
FormatPurified
Presentation0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Quality LevelMQ100
Applications
ApplicationAnti-Mps1 Antibody, CT, clone 4-112-3 is a high quality Mouse Monoclonal Antibody for the detection of Mps1 & has been validated in IP, WB, ICC.
Key Applications
  • Immunoprecipitation
  • Western Blotting
  • Immunocytochemistry
Biological Information
ImmunogenHis-tagged fusion protein corresponding to amino acids 3-856 of human Mps1
Cloneclone 4-112-3
HostMouse
SpecificityMps1
IsotypeIgG
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • TTK
  • PYT
  • MPS1L1
  • ESK
  • FLJ38280
Purification MethodProtein G Chromatography
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P33981 # Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation.
SIZE: 857 amino acids; 97072 Da
TISSUE SPECIFICITY: Present in rapidly proliferating cell lines.
SIMILARITY: SwissProt: P33981 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
Molecular Weight97kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assuranceroutinely evaluated by immunoblot on HeLa total cell extract
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions2 years at -20°C
Packaging Information
Material Size200 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
05-683 04053252471278

Documentation

Anti-Mps1 Antibody, CT, clone 4-112-3 MSDS

Title

Safety Data Sheet (SDS) 

Anti-Mps1 Antibody, CT, clone 4-112-3 Certificates of Analysis

TitleLot Number
Anti-Mps1, CT, clone 4-112-3 (mouse monoclonal IgG1) 3090796
Anti-Mps1, CT, clone 4-112-3 (mouse monoclonal IgG1) 2899918
Anti-Mps1, CT, clone 4-112-3 (mouse monoclonal IgG1) - 2250526 2250526
Anti-Mps1, CT, clone 4-112-3 (mouse monoclonal IgG1) - 2361826 2361826
Anti-Mps1, CT, clone 4-112-3 - 22462 22462
Anti-Mps1, CT, clone 4-112-3 - 3164847 3164847
Anti-Mps1, CT, clone 4-112-3 - 3708801 3708801
Anti-Mps1, CT, clone 4-112-3 - 4008086 4008086
Anti-Mps1, CT, clone 4-112-3 - DAM1564471 DAM1564471
Anti-Mps1, CT, clone 4-112-3 - DAM1731736 DAM1731736
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References

Reference overviewPub Med ID
Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication.
Stucke, Volker M, et al.
EMBO J., 21: 1723-32 (2002)  2002

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