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AB9213 Anti-Metabotropic Glutamate Receptor 7 Antibody

Detect Metabotropic Glutamate Receptor 7 using this Anti-Metabotropic Glutamate Receptor 7 Antibody validated for use in IH(P) & WB.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neurotransmitters & Receptors Gene Symbol: GRM7, mGlu7, GPRC1G, FLJ40498, mGluR7, MGLUR7, GLUR7 UniProt Number: Q14831
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AB9213
50 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HIH(P), WBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberAB9213
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Metabotropic Glutamate Receptor 7 Antibody
References
Product Information
FormatAffinity Purified
PresentationAffinity purified immunoglobulin. Liquid in PBS 0.01% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect Metabotropic Glutamate Receptor 7 using this Anti-Metabotropic Glutamate Receptor 7 Antibody validated for use in IH(P) & WB.
Key Applications
  • Immunohistochemistry (Paraffin)
  • Western Blotting
Application NotesWestern blot

Immunohistochemistry on formalin fixed paraffin embedded tissue sections.

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenSynthetic peptide from the N-terminal extracellular domain of human Metabotropic Glutamate Receptor 7. The immunogen has 100% homology with rat.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityRecognizes Metabotropic Glutamate Receptor 7 [mGluR7].
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Entrez Gene SummaryL-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternative splice variants of GRM8 have been described but their full-length nature has not been determined.
Gene Symbol
  • GRM7
  • mGlu7
  • GPRC1G
  • FLJ40498
  • mGluR7
  • MGLUR7
  • GLUR7
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q14831 # Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity.
SIZE: 915 amino acids; 102251 Da
SUBUNIT: Interacts with PRKCABP (By similarity).
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed in many areas of the brain, especially in the cerebral cortex, hippocampus, and cerebellum. Expression of GRM7 isoforms in non-neuronal tissues appears to be restricted to isoform 3 and isoform 4.
SIMILARITY: SwissProt: Q14831 ## Belongs to the G-protein coupled receptor 3 family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Availability by Geography
  • This product is not available for sale in Japan.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size50 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB9213 04053252743610

Documentation

Anti-Metabotropic Glutamate Receptor 7 Antibody MSDS

Title

Safety Data Sheet (SDS) 

Anti-Metabotropic Glutamate Receptor 7 Antibody Certificates of Analysis

TitleLot Number
RABBIT ANTI-METABOTROPIC GLUTAMATE RECEPTOR 7 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2123635 2123635
RABBIT ANTI-METABOTROPIC GLUTAMATE RECEPTOR 7 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2378171 2378171
RABBIT ANTI-METABOTROPIC GLUTAMATE RECEPTOR 7 - 3179236 3179236
RABBIT ANTI-METABOTROPIC GLUTAMATE RECEPTOR 7 AFFINITY PURIFIED POLYCLONAL ANTIBODY 2885979
RABBIT ANTI-METABOTROPIC GLUTAMATE RECEPTOR 7 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2227108 2227108
RABBIT ANTI-METABOTROPIC GLUTAMATE RECEPTOR 7 AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2280280 2280280

Data Sheet

Title
RABBIT ANTI- METABOTROPIC GLUTAMATE RECEPTOR 7 AFFINITY PURIFIED POLYCLONAL ANTIBODY