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MABN153 Anti-HuC/HuD Antibody, clone 15A7.1

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MABN153
100 µg  
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Overview

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, R, MWB, IH(P)MPurifiedMonoclonal Antibody
Description
Catalogue NumberMABN153
DescriptionAnti-HuC/HuD Antibody, clone 15A7.1
Alternate Names
  • ELAV-like protein 3
  • Hu-antigen C
  • HuC
  • Paraneoplastic cerebellar degeneration-associated antigen
  • Paraneoplastic limbic encephalitis antigen 21
  • ELAV-like protein 4
  • Hu-antigen D
  • HuD
  • Paraneoplastic encephalomyelitis antigen HuD
Background InformationHu proteins are mammalian embryonic lethal abnormal visual system (ELAV)-like neuronal RNA-binding proteins that contain three RNA recognition motifs. RNA binding protein HuC promotes neuronal development in both the central and the peripheral nervous systems. HuC antibodies are used as markers for developing neurons. HuD may play a role in neuron-specific RNA processing, and be involved in maintaining the proliferative state of cells.
Product Information
FormatPurified
Control
  • Human brain tissue lysate
PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis HuC/HuD antibody is validated for use in WB & IHC for the detection of the HuC/HuD protein.
Key Applications
  • Western Blotting
  • Immunohistochemistry (Paraffin)
Application NotesImmunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected HuC/HuD in human brain and rat hippocampus tissues.
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human HuC/HuD.
Clone15A7.1
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
IsotypeIgG2aκ
Species Reactivity
  • Human
  • Rat
  • Mouse
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • ELAVL3
  • HUC
  • PLE21
  • ELAVL4
  • HUD
  • PNEM
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~ 40 kDa observed. An uncharacterized band may appear at ~45 kDa in some lysates.
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in human brain tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected HuC/HuD in 200 µg of human brain tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Global Trade Item Number
Catalogue Number GTIN
MABN153 04053252858307