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MABF271 Anti-FPR1/2 Antibody, clone NFPR1

Anti-FPR1/2 Antibody, clone NFPR1 is an antibody against FPR1/2 for use in Western Blotting, Flow Cytometry, Immunocytochemistry, Immunoprecipitation.

Anti-FPR1/2 Antibody, clone NFPR1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: FPR1 UniProt Number: P21462
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MABF271
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWB, FC, ICC, IPMPurifiedMonoclonal Antibody
Description
Catalogue NumberMABF271
DescriptionAnti-FPR1/2 Antibody, clone NFPR1
Alternate Names
  • Anti-Formyl Peptide Receptor 1/2
  • FMLP1/2
  • fMet-Leu-Phe receptor
  • fMLP receptor
  • N-formyl peptide receptor
  • FPR
  • N-formylpeptide chemoattractant receptor
Background InformationN-formy peptide receptor 1 (also known as N-formylpeptide chemoattractant receptor or fMet-Leu-Phe receptor) & 2 (also known as RFP, FMLP-R-I, Lipoxin A4 receptor, LXA4 receptor, FMLP-related receptor I, Formyl peptide receptor-like 1) are multi-pass cell membrane G protein-coupled receptors (GPCRs) encoded by the FPR1 (also known as FPR and FMLP) and FPR2 (also known as FPR2 and FMLP-R-II) gene in human, respectively. The FPR1 gene encodes the high-affinity, and FPR2 the low-affinity, receptor for N-formyl-methionyl peptides (FMLP). Both receptors mediate FMLP-induced activation of neutrophils.
References
Product Information
FormatPurified
PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-FPR1/2 Antibody, clone NFPR1 is an antibody against FPR1/2 for use in Western Blotting, Flow Cytometry, Immunocytochemistry, Immunoprecipitation.
Key Applications
  • Western Blotting
  • Flow Cytometry
  • Immunocytochemistry
  • Immunoprecipitation
Application NotesFlow Cytometry Analysis: A representative lot detected FPR1/2 in human neutraphils (Riesselman, M., et al. (2007). J. Immunol. 179:2520-2531).
Immunocytochemistry Analysis: A representative lot detected FPR1/2 in human neutraphils (Riesselman, M., et al. (2007). J. Immunol. 179:2520-2531).
Immunoprecipitation Analysis: A representative lot immunoprecipitated FPR1/2 in neutraphils (Maaty, W.S., et al. (2013). JBC. 288(38):27042-27058).
Western Blotting Analysis: A representative lot detected FPR1/2 in neutraphils (Maaty, W.S., et al. (2013). JBC. 288(38):27042-27058).
Biological Information
ImmunogenHis-tagged recombinant protein corresponding to the FPR1 (305-GQDFRERLI-313) and FPR2 (306- GQDFRERLI-314) of human FPR1/2.
EpitopeFPR1 (305-GQDFRERLI-313) and FPR2 (306- GQDFRERLI-314)
CloneNFPR1
ConcentrationPlease refer to lot specific datasheet.
HostMouse
SpecificityThis antibody is epitope mapped, recognizing cytoplasmic c-terminal tail residues of FPR1 (305-GQDFRERLI-313) and of FPR2 (306- GQDFRERLI-314) (Riesselman, M., et al. (2007). J. Immunol. 179:2520-2531).
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Gene Symbol
  • FPR1
Purification MethodProtein G Purified
UniProt Number
Molecular Weight~38 kDa observed. Uncharacterized band(s) may appear in some lysates.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in THP-1 cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected FPR1/2 in 10 µg of THP-1 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABF271 04055977159318