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AB15467 Anti-ARG3.1 Antibody

Detect ARG3.1 using this Anti-ARG3.1 Antibody validated for use in IH.

Anti-ARG3.1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Neuronal & Glial Markers, Synapse & Synaptic Biology Gene Symbol: ARC, KIAA0278, Arg3.1, NOP, NOL3, ARC/ARG3.1, MYC UniProt Number: Q7LC44
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AB15467
50 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
RIHCRbSerumPolyclonal Antibody
Description
Catalogue NumberAB15467
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-ARG3.1 Antibody
Alternate Names
  • Anti-Growth Factor ARC
  • Activity Regulated Cytoskeleton
Background InformationArc/Arg3.1 is an immediate-early gene whose mRNA is rapidly transcribed and targeted to dendrites of neurons as they engage in information processing and storage. Arc/Arg3.1 is known to be required for durable forms of synaptic plasticity and learning. Arc/Arg3.1 has been shown to be expressed in neuronal cell bodies and dendrites in the brain regions including striatum and cortex hippocampus.
References
Product Information
FormatSerum
PresentationLyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative.
Quality LevelMQ100
Applications
ApplicationDetect ARG3.1 using this Anti-ARG3.1 Antibody validated for use in IH.
Key Applications
  • Immunohistochemistry
Application NotesImmunohistochemistry: 1:200-1:1,000

Optimal working dilutions must be determined by end user.
Biological Information
ImmunogenSynthetic peptide corresponding to a region within the C-terminus of human ARG3.1 protein.
HostRabbit
SpecificityARG3.1 [Growth factor ARC, Activity regulated cytoskeleton]
Species Reactivity
  • Rat
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • ARC
  • KIAA0278
  • Arg3.1
  • NOP
  • NOL3
  • ARC/ARG3.1
  • MYC
Purification MethodSerum
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q7LC44 # Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity).
SIZE: 396 amino acids; 45316 Da
SUBUNIT: Interacts with SH3GL1/endophilin-2, SH3GL3/endophilin-3 and DNM2/DYN2 (By similarity).
SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton (By similarity). Endosome (By similarity). Acrosome (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity). Cell projection, dendrite (By similarity). Cell projection, dendritic spine (By similarity). Cell junction, synapse (By similarity). Note=Associated with the cell cortex of neuronal soma and dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail (By similarity).
SIMILARITY: SwissProt: Q7LC44 ## Belongs to the ARC/ARG3.1 family.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.
Packaging Information
Material Size50 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
AB15467 04053252406959

Documentation

Anti-ARG3.1 Antibody MSDS

Title

Safety Data Sheet (SDS) 

Anti-ARG3.1 Antibody Certificates of Analysis

TitleLot Number
RABBIT ANTI-ARG3.1 POLYCLONAL ANTIBODY - 2378680 2378680
RABBIT ANTI-ARG3.1 - 3189261 3189261
RABBIT ANTI-ARG3.1 POLYCLONAL ANTIBODY - 2228115 2228115

References

Reference overviewPub Med ID
Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors
Shepherd, Jason D, et al
Neuron, 52:475-84 (2006)  2006

17088213 17088213

Data Sheet

Title
RABBIT ANTI-ARG3.1 POLYCLONAL ANTIBODY

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Alternative Format

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Categories

Life Science Research > Antibodies and Assays > Primary Antibodies