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116802 Adenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt - CAS 30275-80-0 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
30275-80-0C₁₇H₁₅N₅O₇P · Na

Products

Catalogue NumberPackaging Qty/Pack
116802-10UMOLCN 玻璃瓶 10 umol
Description
OverviewA potent cell-permeable activator of cAMP-dependent protein kinase (PKA). Activates both type 1 and type 2 PKA and binds to the cAMP binding site 2 on the regulatory subunit of PKA. It is only slowly metabolized by cyclic nucleotide-dependent phosphodiesterases. Due to its considerably increased lipophilicity, it has sufficient membrane permeability for many biological systems.
Note: 10 µmol = 4.55 mg.
Catalogue Number116802
Brand Family Calbiochem®
Synonyms6-Bnz-cAMP, Na
References
ReferencesDøskeland, S.O., et al. 1993. Biochim. Biophys. Acta 1178, 249.
Laurent-Cadoret, V., et al. 1993. Acta Endocrinol. 128, 555.
Zorn, M., et al. 1993. Eur. J. Cell Biol. 60, 351.
Product Information
CAS number30275-80-0
ATP CompetitiveN
FormLyophilized
Hill FormulaC₁₇H₁₅N₅O₇P · Na
Chemical formulaC₁₇H₁₅N₅O₇P · Na
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
ApplicationAdenosine 3ʹ,5ʹ-cyclic Monophosphate, N⁶-Benzoyl-, Sodium Salt, CAS 30275-80-0, is a cell-permeable, potent activator of PKA type 1 & 2. Binds to the cAMP binding site 2 on the regulatory unit of PKA.
Biological Information
Primary TargetPKA
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Global Trade Item Number
Catalogue Number GTIN
116802-10UMOLCN 04055977208207