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05-23-0600 Substance P - CAS 33507-63-0 - Calbiochem

Neuropeptide found in high concentrations in the gut.

Substance P - CAS 33507-63-0 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: RPKPQQFFGLM

Primary Target: Substance P receptors
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Overview

Key Spec Table

CAS #Empirical Formula
33507-63-0C₆₃H₉₈N₁₈O₁₃S

Products

Catalogue NumberPackaging Qty/Pack
05230600-1MGCN Plastic ampoule 1 mg
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05230600-25MGCN Plastic ampoule 25 mg
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05230600-5MGCN Plastic ampoule 5 mg
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Description
OverviewNeuropeptide found in high concentrations in the gut. When released from afferent nerves, causes a neurogenic inflammatory response, including mast cell degranulation. Induces Ca2+ mobilization. Reported to activate Goα, Gq/11α, and Gsα subunits in CHO cells via activation of substance P receptors. Also reported to induce superoxide production in neutrophils.
Catalogue Number05-23-0600
Brand Family Calbiochem®
SynonymsRPKPQQFFGLM
References
ReferencesRoush, E.D., and Kwatra, M.M. 1998. FEBS Lett. 428, 291.
Chiwakata, C.B., et al. 1996. Infect. Immun. 64, 5106.
Tanabe, T., et al. 1996. Eur. J. Pharmacol. 299, 187.
Heath, M.J., et al. 1994. J. Neurophysiol. 72, 1192.
Zhu, J., et al. 1994. Eur. J. Pharmacol. 268, 279.
Garland, A.M., et al. 1993. Soc. Neurosci. 19, Abstract 104.6.
Wei, J.Y., et al. 1993. Soc. Neurosci. 19, Abstract 136.14.
Product Information
CAS number33507-63-0
ATP CompetitiveN
FormWhite solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₆₃H₉₈N₁₈O₁₃S
Chemical formulaC₆₃H₉₈N₁₈O₁₃S
Hygroscopic Hygroscopic
ReversibleN
Sold on the basis of peptide contentY
Quality LevelMQ100
Biological Information
Primary TargetSubstance P receptors
Purity≥96% by HPLC
Physicochemical Information
Cell permeableN
Peptide ContentY
Peptide SequenceH-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH₂
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Global Trade Item Number
Catalogue Number GTIN
05230600-1MGCN 04055977207019
05230600-25MGCN 04055977207026
05230600-5MGCN 04055977207033