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5677 Spermine, Tetrahydrochloride - CAS 306-67-2 - Calbiochem

Polyamine that plays an important role in the regulation of cellular proliferation and differentiation.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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5677
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Overview

Key Spec Table

CAS #Empirical Formula
306-67-2C₁₀H₂₆N₄ . 4HCl

Products

Catalogue NumberPackaging Qty/Pack
5677-5GMCN Plastic ampoule 5 gm
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Description
OverviewPolyamine that plays an important role in the regulation of cellular proliferation and differentiation. Has both stimulatory and inhibitory effects on NMDA receptors depending on the subunit composition of the receptor. Acts as an inhibitor of phospholipase Cα and an activator of phospholipase Cδ. Inhibits DNA fragmentation and morphological apoptosis. Inhibits neuronal NOS.
Catalogue Number5677
Brand Family Calbiochem®
References
ReferencesIgarashi, K. and Williams, K. 1995. J. Pharmacol. Exp. Ther. 272, 1101.
Escargueil-Blanc, I., et al. 1994. FASEB J. 8, 1075.
Hu, J., et al. 1994. Neurosci. Lett. 175, 41.
Tompkins, T.A. and Moscarello, M.A. 1994. Biochim. Biophys. Acta 1206, 1208.
Trubiani, O., et al. 1994. Biochem. Mol. Biol. Int. 32, 1085.
Svensson, F., et al. 1993. Mol. Cell. Biochem. 124, 141.
Ask, A., et al. 1992. Cancer Lett. 66, 29.
Chida, N., et al. 1992. Brain Res. 593, 57.
Khan, A.U., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 11428.
Messena, L., et al. 1992. J. Leukoc. Biol. 52, 585.
Pawelczyk, T., et al. 1992. Arch. Biochem. Biophys. 297, 328.
Shantz, L.M., et al. 1992. Biochem. J. 288, 511.
Product Information
CAS number306-67-2
FormWhite solid
Hill FormulaC₁₀H₂₆N₄ . 4HCl
Chemical formulaC₁₀H₂₆N₄ . 4HCl
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary Targetphospholipase C α
Secondary targetnNOS
Purity≥99% by titration
Safety Information according to GHS
RTECSEJ7230000
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C under inert gas.
Global Trade Item Number
Catalogue Number GTIN
5677-5GMCN 04055977190939