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538904 Prostaglandin E₂ - CAS 363-24-6 - Calbiochem

Prostaglandin E₂, CAS 363-24-6, is a product of arachidonic acid metabolism that binds to EP1, EP2, EP3, & EP4 receptors with high affinity (Kd = 1-10 nM). Involved in vasodilator actions of kinins.

Prostaglandin E₂ - CAS 363-24-6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: PGE₂

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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
363-24-6C₂₀H₃₂O₅

Products

Catalogue NumberPackaging Qty/Pack
538904-1MGCN Plastic ampoule 1 mg
Description
OverviewInvolved in vasodilator actions of kinins such as bradykinin. Inhibits MAP kinase in rat mesangial cells (IC50 = 25-50 µM). Regulates the activity of adenylate cyclase via G-protein coupled receptors.
Catalogue Number538904
Brand Family Calbiochem®
SynonymsPGE₂
References
ReferencesLi, X., et al. 1995. Am. J. Physiol. 269, C986.
Kessler, W., et al. 1992. Exp. Brain Res. 91, 467.
Product Information
CAS number363-24-6
ATP CompetitiveN
FormWhite to light yellow solid
Hill FormulaC₂₀H₃₂O₅
Chemical formulaC₂₀H₃₂O₅
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
ApplicationProstaglandin E₂, CAS 363-24-6, is a product of arachidonic acid metabolism that binds to EP1, EP2, EP3, & EP4 receptors with high affinity (Kd = 1-10 nM). Involved in vasodilator actions of kinins.
Biological Information
Primary TargetInvolved in vasodilator actions of kinins such as bradykinin
Primary Target IC<sub>50</sub>25-50 µM inhibiting MAP kinase in rat mesangial cells
Purity>98% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSUK8000000
Safety Information
R PhraseR: 20/21/22

Harmful by inhalation, in contact with skin and if swallowed.
S PhraseS: 22-36

Do not breathe dust.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Harmful
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
538904-1MGCN 07790788051266

Documentation

Prostaglandin E₂ - CAS 363-24-6 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Prostaglandin E₂ - CAS 363-24-6 - Calbiochem Certificates of Analysis

TitleLot Number
538904

References

Reference overview
Li, X., et al. 1995. Am. J. Physiol. 269, C986.
Kessler, W., et al. 1992. Exp. Brain Res. 91, 467.

Brochure

Title
Activators and Inhibitors of Adenylate Cyclase Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-June-2013 JSW
SynonymsPGE₂
DescriptionInvolved in vasodilator actions of kinins such as bradykinin. Inhibits MAP kinase in rat mesangial cells (IC50 = 25-50 µM). Regulates the activity of adenylate cyclase via G-protein coupled receptors.
FormWhite to light yellow solid
CAS number363-24-6
RTECSUK8000000
Chemical formulaC₂₀H₃₂O₅
Structure formulaStructure formula
Purity>98% by HPLC
SolubilityAcetone, ethanol, methanol, or ethyl acetate
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Toxicity Harmful
Merck USA index14, 7877
ReferencesLi, X., et al. 1995. Am. J. Physiol. 269, C986.
Kessler, W., et al. 1992. Exp. Brain Res. 91, 467.