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528178 Plasminogen, EACA- and Lysine-Free, Human Plasma

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Profibrinolysin, Plasma Trypsinogen

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528178
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Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
528178-50UCN Plastic ampoule 50 u
Description
OverviewNative plasminogen (EACA- and lysine-free) from human plasma. Plasminogen is a single chain glycoprotein found in normal plasma at ~12 mg per deciliter, and is the inactive precursor of the serine protease plasmin.
Catalogue Number528178
Brand Family Calbiochem®
SynonymsProfibrinolysin, Plasma Trypsinogen
References
ReferencesSun, Z., et al. 2002. Biochim. Biophys. Acta 1596, 182.
Robbins, K.C., et al. 1967. J. Biol. Chem. 242, 2333.
Product Information
CAS number9001-91-6
Unit of DefinitionOne unit is defined as the amount of enzyme that will hydrolyze 1 µmol of N-tosyl-Gly-Pro-Lys-<i>p</i>NA per min at 25°C, pH 7.8.
FormLyophilized
FormulationLyophilized from 20 mM sodium phosphate buffer, 10 mg D-mannitol, 10 mg NaCl.
Quality LevelMQ100
Applications
Biological Information
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Specific Activity7 units/mg protein
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for at least 1 week at 4°C or for 1-2 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
528178-50UCN 04055977196443

Documentation

Plasminogen, EACA- and Lysine-Free, Human Plasma SDS

Title

Safety Data Sheet (SDS) 

Plasminogen, EACA- and Lysine-Free, Human Plasma Certificates of Analysis

TitleLot Number
528178

References

Reference overview
Sun, Z., et al. 2002. Biochim. Biophys. Acta 1596, 182.
Robbins, K.C., et al. 1967. J. Biol. Chem. 242, 2333.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision03-November-2008 JSW
SynonymsProfibrinolysin, Plasma Trypsinogen
DescriptionNative plasminogen (EACA- and lysine-free) from human plasma. Single chain glycoprotein containing 790 amino acid residues. Found in normal plasma at about 12 mg/100 ml. Inactive precursor of the serine protease plasmin. It is converted to the active protease by cleavage at Arg560.
FormLyophilized
FormulationLyophilized from 20 mM sodium phosphate buffer, 10 mg D-mannitol, 10 mg NaCl.
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
CAS number9001-91-6
Specific activity7 units/mg protein
Unit definitionOne unit is defined as the amount of enzyme that will hydrolyze 1 µmol of N-tosyl-Gly-Pro-Lys-pNA per min at 25°C, pH 7.8.
SolubilityH₂O
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for at least 1 week at 4°C or for 1-2 months at -20°C.
Toxicity Irritant
Merck USA index14, 7521
ReferencesSun, Z., et al. 2002. Biochim. Biophys. Acta 1596, 182.
Robbins, K.C., et al. 1967. J. Biol. Chem. 242, 2333.