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100482 Periodic acid solution 0.5%

for the PAS reaction for the detection of aldehyde and mucosubstances in microscopy

Periodic acid solution 0.5% MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
100482
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Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
1.00482.1000 Plastic bottle 1 l
Description
Catalogue Number100482
DescriptionPeriodic acid solution 0.5%
OverviewThe Periodic acid solution 0.5% for the PAS reaction(periodic acid Schiff) for the detection of aldehyde and mucosubstances in microscopy, is a ready to use solution used for the detection of mucopolysaccharides, glycogen, muco- and glycoproteins, glyco-, phospholipids, basal membranes and collagen. The material is treated with periodic acid creating aldehyde groups which react with Schiff's reagent and give a bright red color reaction, thus the nuclei appear blue.
In the PAS reaction, the histological specimen material is first treated with periodic acid, resulting in the oxidation of the 1,2-glycols into aldehyde groups. The addition of Schiff’s reagent (fuchsin-sulfuric acid)(Cat.no. 109033) in the second step causes the aldehydes to react to form a brilliant red color. In the end result, the PAS reaction yields a specific color reaction with unsubstituted polysaccharides, neutral mucopolysaccharides, muco- and glycoproteins, and glyco- and phospholipids.
The PAS reaction can be further combined with the Alcian blue staining method to detect mucosubstances (glycosaminoglycans).
It is an IVD / CE registered & certified product that can be applied in clinical diagnostics due to its excellent quality. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
References
Product Information
HS Code2811 19 80
Quality LevelMQ400
Applications
Applicationfor the PAS reaction for the detection of aldehyde and mucosubstances in microscopy
Biological Information
Physicochemical Information
Density1.002 g/cm3 (20 °C)
pH value2.1 (H₂O)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Hazard Statement(s)H412: Harmful to aquatic life with long lasting effects.
Precautionary Statement(s)P273: Avoid release to the environment.
P501: Dispose of contents/ container to an approved waste disposal plant.
Storage class10 - 13 Other liquids and solids
WGKWGK 2 obviously hazardous to water
Disposal12
Inorganic acids and anhydrides thereof should first be diluted or hydrolyzed by stirring carefully into ice water and then neutralized (protective gloves, fume cupboard!) with sodium hydroxide solution (Cat. No. 105587). Before filling into container D, check the pH with pH universal indicator strips (Cat. No. 109535). Fuming sulfuric acid should be carefully stirred dropwise into 40 % sulfuric acid (Cat. No. 109286). Ensure that plenty of ice is available for cooling! When sufficiently cool, treat the highly concentrated sulfuric acid as described above. Analogous to this procedure, other anhydrides can be converted into their corresponding acids. Acid gases (e.g. hydrogen halide, chlorine, phosgene, sulfur dioxide) can be introduced into dilute sodium hydroxide solution and after neutralization disposed of in container D.
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +15°C to +25°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDKein Gefahrgut
Declaration (transport by air) IATA-DGRNo Dangerous Good
Declaration (transport by sea) IMDG-CodeNo Dangerous Good
Supplemental Information
Specifications
Nucleiblue
Polysaccharidespurple
Glycogenpurple
Neutral mucopolysaccharidespurple
Mucoproteinspurple
Glycoproteinspurple
Glycolipidspurple
Phospholipidspurple
Basement membranepurple
Collagenpurple
Global Trade Item Number
Catalogue Number GTIN
1.00482.1000 04022536706726