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480030 NEMO-Binding Domain Binding Peptide, Cell-Permeable, Negative Control - Calbiochem

A cell-permeable Antennapedia-NBD mutated fusion peptide analog of NEMO-Binding Domain Binding Peptide that serves as a negative control.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: DRQIKIWFQNRRMKWKK-TALDASALQTE, NBD-Binding Peptide, Cell-Permeable, Negative Control

Primary Target: Negative control defective in binding to NEMO
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480030
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Overview

Key Spec Table

Empirical Formula
C₁₅₄H₂₄₉N₄₇O₄₂S

Products

Catalogue NumberPackaging Qty/Pack
480030-500UGCN Plastic ampoule 500 μg
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Description
OverviewA cell-permeable Antennapedia-NBD mutated (Trp739 and Trp741 replaced with Ala) fusion peptide analog of NEMO-Binding Domain Binding Peptide (Cat. No. 480025) that serves as a negative control. Shown to be defective in binding to NEMO. Does not affect the TNF-α-induced phosphorylation of c-Jun and DNA binding of the transcription factor Oct-1.
Catalogue Number480030
Brand Family Calbiochem®
SynonymsDRQIKIWFQNRRMKWKK-TALDASALQTE, NBD-Binding Peptide, Cell-Permeable, Negative Control
References
ReferencesJimi, E., et al. 2004. Nat. Med., 10, 617.
May, M.J., et al. 2000. Science 289, 1550.
Product Information
ATP CompetitiveN
FormLyophilized off-white solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₁₅₄H₂₄₉N₄₇O₄₂S
Chemical formulaC₁₅₄H₂₄₉N₄₇O₄₂S
Hygroscopic Hygroscopic
ReversibleN
Quality LevelMQ100
Biological Information
Primary TargetNegative control defective in binding to NEMO
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Peptide SequenceH₂N-Asp-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Thr-Ala-Leu-Asp-Ala-Ser-Ala-Leu-Gln-Thr-Glu-OH
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Catalogue Number GTIN
480030-500UGCN 04055977201857