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203995 N-tert-Butyl-α-phenylnitrone - CAS 3376-24-7 - Calbiochem

Most commonly-used free radical trap.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: PBN

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203995
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
3376-24-7C₁₁H₁₅NO

Products

Catalogue NumberPackaging Qty/Pack
203995-500MGCN Plastic ampoule 500 mg
Description
OverviewMost commonly-used free radical trap. An antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative disorders. Inhibits lipid peroxidation in rat liver microsomes. Also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.
Catalogue Number203995
Brand Family Calbiochem®
SynonymsPBN
References
ReferencesFloyd, R.A. 1997. Adv. Pharmacol. 38, 361.
Miyajima, T., and Kotake, Y. 1995. Biochem. Biophys. Res. Commun. 215, 114.
Jazen, E.G., et al. 1994. in Frontiers of Reactive Oxygen Species in Biology and Medicine, (Asada, K., and Yoshikawa, T., eds.), pp. 431-434. Elsevier Science, Amsterdam.
Floyd, R.A. 1990. FASEB J. 4, 2587.
Product Information
CAS number3376-24-7
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₁H₁₅NO
Chemical formulaC₁₁H₁₅NO
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetFree radical trap
Purity≥98% by GC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution in DMSO aliquot and freeze (-20°C). Stock solutions in DMSO are stable for up to 2 months at -20°C. Unstable in aqueous solution; reconstitute just prior to use.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
203995-500MGCN 04055977220018

Documentation

N-tert-Butyl-α-phenylnitrone - CAS 3376-24-7 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

N-tert-Butyl-α-phenylnitrone - CAS 3376-24-7 - Calbiochem Certificates of Analysis

TitleLot Number
203995

References

Reference overview
Floyd, R.A. 1997. Adv. Pharmacol. 38, 361.
Miyajima, T., and Kotake, Y. 1995. Biochem. Biophys. Res. Commun. 215, 114.
Jazen, E.G., et al. 1994. in Frontiers of Reactive Oxygen Species in Biology and Medicine, (Asada, K., and Yoshikawa, T., eds.), pp. 431-434. Elsevier Science, Amsterdam.
Floyd, R.A. 1990. FASEB J. 4, 2587.

Brochure

Title
Pathways and Biomarkers of Oxidative Stress
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision22-May-2008 RFH
SynonymsPBN
DescriptionMost commonly used free radical trap. An antioxidant that has been shown to act as a protective agent in several experimental models of neurodegenerative diseases. Inhibits lipid peroxidation in rat liver microsomes. Also prevents the induction of inducible nitric oxide synthase (iNOS) by reactive oxygen species.
FormWhite solid
CAS number3376-24-7
Chemical formulaC₁₁H₁₅NO
Structure formulaStructure formula
Purity≥98% by GC
SolubilityDMSO (10 mg/ml), H₂O (20 mg/ml), or Chloroform (50 mg/ml)
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution in DMSO aliquot and freeze (-20°C). Stock solutions in DMSO are stable for up to 2 months at -20°C. Unstable in aqueous solution; reconstitute just prior to use.
Toxicity Standard Handling
ReferencesFloyd, R.A. 1997. Adv. Pharmacol. 38, 361.
Miyajima, T., and Kotake, Y. 1995. Biochem. Biophys. Res. Commun. 215, 114.
Jazen, E.G., et al. 1994. in Frontiers of Reactive Oxygen Species in Biology and Medicine, (Asada, K., and Yoshikawa, T., eds.), pp. 431-434. Elsevier Science, Amsterdam.
Floyd, R.A. 1990. FASEB J. 4, 2587.