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FCMAB180F Milli-Mark™ Anti-CD13-FITC Antibody, clone WM-47

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FCMAB180F
100 tests  
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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HFCMFITCMonoclonal Antibody
Description
Catalogue NumberFCMAB180F
Trade Name
  • Milli-Mark
DescriptionMilli-Mark™ Anti-CD13-FITC Antibody, clone WM-47
Alternate Names
  • Aminopeptidase N (AP-N), hAPN, Alanyl aminopeptidase, Microsomal aminopeptidase, Aminopeptidase M (AP-M), gp150, Myeloid plasma membrane glycoprotein CD13
Background InformationCD13 is a 150 kDa Type II integral membrane protein composed of 967 amino acids (Turni, 2002; Ashmun, 1995; Look, 1989). CD13 is identical in structure to aminopeptidase N, a membrane-bound zinc-binding metalloprotease (Turni, 2002). CD13 is expressed on the surface of committed granulocyte-monocyte progenitors (CFU-GM) and by cells of the granulocyte and monocyte lineages at all stages of differentiation (Turni, 2002; Ashmun, 1995; Look, 1989). The antigen is also expressed on a small proportion of large granular lymphocytes, but not on B or T cells (Ashmun, 1995; Look, 1989). Further, CD13 is expressed on some non-hematopoietic cells including fibroblasts, endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining the bile duct canaliculi (Turni, 2002; Ashmun, 1995; Look, 1989).
Anti-CD13, WM-47, was included in the Fourth and Fifth International Workshop and Conference on Leucocyte Differentiation Antigens and studies by a number of laboratories confirmed its reactivity with CD 13 (Ashmun, 1995; Look, 1989).
References
Product Information
FormatFITC
Control
  • PBMCs
PresentationPurified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
Quality LevelMQ100
Applications
ApplicationDetect CD13 using this Milli-Mark Anti-CD13-FITC Antibody, clone WM-47 validated for use in FC.
Key Applications
  • Flow Cytometry
Biological Information
ImmunogenLeukaemic cells from a case of chronic myeloid leukaemia (CML).
CloneWM-47
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityAntibody recognizes Human CD13 antigen.
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Purification MethodProtein A Purfied
UniProt Number
Molecular Weight 150 kDa (Turni, 2002; Ashmun, 1995; Look, 1989)
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by flow cytometry using human PBMCs
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.
Packaging Information
Material Size100 tests
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
FCMAB180F 04053252289101

Documentation

Milli-Mark™ Anti-CD13-FITC Antibody, clone WM-47 SDS

Title

Safety Data Sheet (SDS) 

Milli-Mark™ Anti-CD13-FITC Antibody, clone WM-47 Certificates of Analysis

TitleLot Number
Milli-Mark Anti-CD13-FITC, clone WM-47 - 2140070 2140070
Milli-Mark Anti-CD13-FITC, clone WM-47 - 2092946 2092946
Milli-Mark Anti-CD13-FITC, clone WM-47 - 2199656 2199656
Milli-Mark Anti-CD13-FITC, clone WM-47 - NG1940534 NG1940534
Milli-Mark Anti-CD13-FITC, clone WM-47 - NRG1761329 NRG1761329
Milli-Mark™ Anti-CD13-FITC, clone WM-47 3076512
Milli-Mark™ Anti-CD13-FITC, -2586534 2586534
Milli-Mark™ Anti-CD13-FITC, -2591349 2591349
Milli-Mark™ Anti-CD13-FITC, -2603848 2603848
Milli-Mark™ Anti-CD13-FITC, -2643582 2643582