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444300 Melatonin - CAS 73-31-4 - Calbiochem

A hormone that has been postulated as the mediator of photo-induced anti-gonadotropic activity in photoperiodic mammals.

Melatonin - CAS 73-31-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: N-Acetyl-5-methoxytryptamine, 5-Methoxy-N-acetyltryptamine

Primary Target: rat NOS
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
73-31-4C₁₃H₁₆N₂O₂

Products

Catalogue NumberPackaging Qty/Pack
444300-1GMCN Plastic ampoule 1 gm
Description
OverviewA hormone that has been postulated as the mediator of photo-induced anti-gonadotropic activity in photoperiodic mammals. Counteracts the apoptotic effects of etoposide in bone marrow cells. Melatonin receptors are coupled to a G-protein system. Exhibits antioxidant properties. Has neuroprotective effects against Aβ peptides. Inhibits rat cerebellar nitric oxide synthase (NOS). Also acts as a peroxynitrite scavenger.
Catalogue Number444300
Brand Family Calbiochem®
SynonymsN-Acetyl-5-methoxytryptamine, 5-Methoxy-N-acetyltryptamine
References
ReferencesPappolla, M.A., et al. 2002. J. Pineal Res. 32, 135.
Reiter, R.J., and Tan, D.X. 2002. Ann. N.Y. Acad. Sci. 957, 341.
Cuzzocrea, S., et al. 1998. J. Pineal Res. 25, 24.
Maestroni, G.J., et al. 1994. Cancer Res. 54, 2429.
Pozo, D., et al. 1994. Life Sciences 55, PL455.
Product Information
CAS number73-31-4
ATP CompetitiveN
FormWhite to slightly yellow powder
Hill FormulaC₁₃H₁₆N₂O₂
Chemical formulaC₁₃H₁₆N₂O₂
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetrat NOS
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSAC5955000
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstiution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
444300-1GMCN 04055977186123

Documentation

Melatonin - CAS 73-31-4 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Melatonin - CAS 73-31-4 - Calbiochem Certificates of Analysis

TitleLot Number
444300

References

Reference overview
Pappolla, M.A., et al. 2002. J. Pineal Res. 32, 135.
Reiter, R.J., and Tan, D.X. 2002. Ann. N.Y. Acad. Sci. 957, 341.
Cuzzocrea, S., et al. 1998. J. Pineal Res. 25, 24.
Maestroni, G.J., et al. 1994. Cancer Res. 54, 2429.
Pozo, D., et al. 1994. Life Sciences 55, PL455.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-February-2018 JSW
SynonymsN-Acetyl-5-methoxytryptamine, 5-Methoxy-N-acetyltryptamine
DescriptionA hormone that has been postulated as being a mediator of photic-induced anti-gonadotropic activity in photoperiodic mammals. Counteracts the apoptotic effects of etoposide in bone marrow cells. Melatonin receptors are coupled to a G-protein system. Inhibits rat cerebellar nitric oxide synthase (NOS).
FormWhite to slightly yellow powder
CAS number73-31-4
RTECSAC5955000
Chemical formulaC₁₃H₁₆N₂O₂
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityMethanol (50 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstiution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
Merck USA index14, 5816
ReferencesPappolla, M.A., et al. 2002. J. Pineal Res. 32, 135.
Reiter, R.J., and Tan, D.X. 2002. Ann. N.Y. Acad. Sci. 957, 341.
Cuzzocrea, S., et al. 1998. J. Pineal Res. 25, 24.
Maestroni, G.J., et al. 1994. Cancer Res. 54, 2429.
Pozo, D., et al. 1994. Life Sciences 55, PL455.