Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

HCYTAAB-17K MILLIPLEX® MAP Human Cytokine Autoantibody Panel

The Human Cytokine Autoantibody panel is a bead-based multiplex assay based on the Luminex xMAP technology which enables the simultaneous analysis of cytokine autoantibodies in human serum and plasma samples.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Multiplexing Detection Methods: Luminex xMAP Research Category: Immune Response Research Sub-Category: Autoimmune disease, Cytokines & Cytokine Receptors, Immune Response, Immune Disorders
View Products on Sigmaaldrich.com
HCYTAAB-17K
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Analytes AvailableSpecies ReactivityKey ApplicationsDetection Methods
BAFF/Blys G-CSF IFNβ IFNγ IL-1α IL-6 IL-8 IL-10 IL-12 (p40) IL-15 IL-17A IL-17F IL-18 IL-22 TNFα HMplexLuminex xMAP
Description
Catalogue NumberHCYTAAB-17K
Trade Name
  • MILLIPLEX
DescriptionMILLIPLEX® MAP Human Cytokine Autoantibody Panel
OverviewThe MILLIPLEX® MAP Human Cytokine Autoantibody Magnetic Bead Panel is a 15-plex kit to be used for the simultaneous detection and profiling of any or all of the following autoantibody analytes in serum and plasma samples: Anti-BAFF, Anti-G-CSF, Anti-IFNβ, Anti-IFNγ, Anti-IL-1α, Anti-IL-6, Anti-IL-8, Anti-IL-10, Anti-IL-12 (p40), Anti-IL-15, Anti-IL-17A, Anti-IL-17F, Anti-IL-18, Anti-IL-22, and Anti-TNFα. For this particular panel, 4 assay control beads are also included as part of the base kit format.
Background InformationAnti-cytokine antibodies occur frequently and are present in healthy individuals and patients with acquired immunodeficiency and autoimmune diseases. Cytokines offering protection against microbes can be targeted by cytokine autoantibodies, leading to life-threatening infections. Some infections associated with anti-cytokine antibodies include M. tuberculosis, Salmonella, S. aureus. E. coli, Histoplasma, and more. The presence of cytokine autoantibodies in autoimmune disease can influence disease severity and activity. These autoimmune diseases may include systemic lupus erythematosus (SLE), multiple sclerosis (MS), Sjögren’s syndrome, rheumatoid arthritis (RA), and acute respiratory distress syndrome. Measuring cytokine autoantibodies may be useful for disease monitoring and efficacy of treatment.
References
Product Information
Detection methodLuminex xMAP
ConfigurationDesign your multiplex kit by choosing available analytes within this panel.
Precision, %
  • Intra-Assay: <15%
  • Inter-assay: <20%
Panel TypeMAGNETIC Immune Response
Applications
ApplicationThe Human Cytokine Autoantibody panel is a bead-based multiplex assay based on the Luminex xMAP technology which enables the simultaneous analysis of cytokine autoantibodies in human serum and plasma samples.
Key Applications
  • Multiplexing
Application Notes• This is assay yields results in Median Fluorescence Intensity (MFI).
• Four assay control beads are included in the base kit.
• This is an overnight or 2 hour incubation assay.
• This assay requires 25 µL of 1:100 diluted plasma or serum.
Biological Information
Species Reactivity
  • Human
Analytes Available
  • BAFF/Blys
  • G-CSF
  • IFNβ
  • IFNγ
  • IL-1α
  • IL-6
  • IL-8
  • IL-10
  • IL-12 (p40)
  • IL-15
  • IL-17A
  • IL-17F
  • IL-18
  • IL-22
  • TNFα
Assay PanelEverything you need in a single kit.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsRecommended storage for kit components is 2 - 8°C.
Packaging Information
Material Size96-well plate
Material Package96 well plate
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
HCYTAAB-17K 04061841213666