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420355 Isoproterenol, Hydrochloride - CAS 51-30-9 - Calbiochem

Phenethylamine derivative.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: β-adrenergic agonist
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420355
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
51-30-9C₁₁H₁₇NO₃ · HCl

Products

Catalogue NumberPackaging Qty/Pack
420355-100MGCN Plastic ampoule 100 mg
Description
OverviewPhenethylamine derivative. Selective β-adrenergic agonist that stimulates adenylate cyclase activity. Promotes glycogen breakdown and causes bronchodilation. Increases Cl– diffusion and potential difference in rabbit trachea cells through nitric oxide generation. Reported to activate MAP Kinase (ERK) by a Rap1 and B-Raf dependent process.
Catalogue Number420355
Brand Family Calbiochem®
References
ReferencesSchmitt, J.M., and Stork, P.J. 2000. J. Biol. Chem. 275, 25342.
Carmena, M.J., et al. 1997. Prostate 33, 46.
Takemura, H., et al. 1995. J. Pharmacol. Exp. Ther. 274, 584.
Kishimoto, I., et al. 1994. J. Biol. Chem. 269, 28300.
Macaulay, S.L., et al. 1994. Mol. Cell Biochem. 141, 27.
Yashiro, K., et al. 1994. J. Biochem. 115, 1040.
Ladenheim, R.G., et al. 1993. J. Neurochem. 60, 260.
von Zastrow, M., et al. 1993. J. Biol. Chem. 268, 763.
Mokhtari, A., et al. 1985. J. Cyclic Nucleotide Protein Phosphorylation Res. 10, 213.
Product Information
CAS number51-30-9
ATP CompetitiveN
FormWhite to off-white solid
Hill FormulaC₁₁H₁₇NO₃ · HCl
Chemical formulaC₁₁H₁₇NO₃ · HCl
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetβ-adrenergic agonist
Purity≥99% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSDO1925000
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage +15°C to +30°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
420355-100MGCN 04055977187533

Documentation

Isoproterenol, Hydrochloride - CAS 51-30-9 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Isoproterenol, Hydrochloride - CAS 51-30-9 - Calbiochem Certificates of Analysis

TitleLot Number
420355

References

Reference overview
Schmitt, J.M., and Stork, P.J. 2000. J. Biol. Chem. 275, 25342.
Carmena, M.J., et al. 1997. Prostate 33, 46.
Takemura, H., et al. 1995. J. Pharmacol. Exp. Ther. 274, 584.
Kishimoto, I., et al. 1994. J. Biol. Chem. 269, 28300.
Macaulay, S.L., et al. 1994. Mol. Cell Biochem. 141, 27.
Yashiro, K., et al. 1994. J. Biochem. 115, 1040.
Ladenheim, R.G., et al. 1993. J. Neurochem. 60, 260.
von Zastrow, M., et al. 1993. J. Biol. Chem. 268, 763.
Mokhtari, A., et al. 1985. J. Cyclic Nucleotide Protein Phosphorylation Res. 10, 213.

Brochure

Title
Activators and Inhibitors of Adenylate Cyclase Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision13-May-2008 RFH
DescriptionPhenethylamine derivative. Selective β-adrenergic agonist that increases cytosolic cAMP. Promotes glycogen breakdown and causes bronchodilation. Increases Cl- diffusion and potential difference in rabbit trachea cells through nitric oxide generation.
FormWhite to off-white solid
CAS number51-30-9
RTECSDO1925000
Chemical formulaC₁₁H₁₇NO₃ · HCl
Structure formulaStructure formula
Purity≥99% by TLC
SolubilityEthanol or H₂O
Storage Protect from light
+15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use.
Toxicity Irritant
Merck USA index14, 5217
ReferencesSchmitt, J.M., and Stork, P.J. 2000. J. Biol. Chem. 275, 25342.
Carmena, M.J., et al. 1997. Prostate 33, 46.
Takemura, H., et al. 1995. J. Pharmacol. Exp. Ther. 274, 584.
Kishimoto, I., et al. 1994. J. Biol. Chem. 269, 28300.
Macaulay, S.L., et al. 1994. Mol. Cell Biochem. 141, 27.
Yashiro, K., et al. 1994. J. Biochem. 115, 1040.
Ladenheim, R.G., et al. 1993. J. Neurochem. 60, 260.
von Zastrow, M., et al. 1993. J. Biol. Chem. 268, 763.
Mokhtari, A., et al. 1985. J. Cyclic Nucleotide Protein Phosphorylation Res. 10, 213.