Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
-MAPmates™ that require a different assay buffer
-Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9)
-PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701)
-More than 1 phospho-MAPmate™ for a single target (Akt, STAT3)
-GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
.
Catalogue Number
Ordering Description
Qty/Pack
List
This item has been added to favorites.
Select A Species, Panel Type, Kit or Sample Type
To begin designing your MILLIPLEX® MAP kit select a species, a panel type or kit of interest.
Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
Catalogue Number
Ordering Description
Qty/Pack
List
This item has been added to favorites.
Species
Panel Type
Selected Kit
Qty
Catalogue Number
Ordering Description
Qty/Pack
List Price
96-Well Plate
Qty
Catalogue Number
Ordering Description
Qty/Pack
List Price
Add Additional Reagents (Buffer and Detection Kit is required for use with MAPmates)
Qty
Catalogue Number
Ordering Description
Qty/Pack
List Price
48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
This item has been added to favorites.
The Product Has Been Added To Your Cart
You can now customize another kit, choose a premixed kit, check out or close the ordering tool.
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More
407653
Sigma-AldrichInterleukin-6 Receptor, Soluble, Human, Recombinant, S. frugiperda
Recombinant, human soluble interleukin-6 receptor expressed in S. frugiperda insect cells. Soluble form of the IL-6 receptor that binds IL-6 and mediates IL-6 signaling through interaction with gp130. Elevated serum levels of soluble IL-6 receptors have been shown to be associated with a number of pathological states including multiple myelomas, adult T cell leukemia, interstitial lung infection, and HIV infection.
Catalogue Number
407653
Brand Family
Calbiochem®
Synonyms
rhIL-6 sR
References
References
Schobitz, B., et al. 1995. FASEB J. 9, 659. Yokoyama, A., et al. 1995. Clin. Exp. Immunol. 100, 325. Suzuki, H., et al. 1993. Eur. J. Immunol. 23, 1078. Lust, J.A., et al. 1992. Cytokine 4, 96. Sugita, T., et al. 1990. J. Exp. Med. 171, 2001. Yamasaki, K., et al. 1988. Science241, 825.
Product Information
Form
Lyophilized
Formulation
Lyophilized from sterile-filtered PBS, 50 µg BSA/µg IL-6 receptor.
ED₅₀= ≥5 ng/ml as measured by its ability to enhance IL-6-induced growth inhibition of mouse M1 myeloid leukemic cells
Purity
≥97% by SDS-PAGE
Physicochemical Information
Contaminants
Endotoxin: ≤1 EU/µg
Storage and Shipping Information
Ship Code
Ambient Temperature Only
Toxicity
Standard Handling
Storage
≤ -70°C
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C. Avoid freeze/thaw cycles of solutions.
Global Trade Item Number
Catalogue Number
GTIN
407653-25UGCN
04055977211412
Documentation
Interleukin-6 Receptor, Soluble, Human, Recombinant, S. frugiperda SDS
Interleukin-6 Receptor, Soluble, Human, Recombinant, S. frugiperda Certificates of Analysis
Title
Lot Number
407653
References
Reference overview
Schobitz, B., et al. 1995. FASEB J. 9, 659. Yokoyama, A., et al. 1995. Clin. Exp. Immunol. 100, 325. Suzuki, H., et al. 1993. Eur. J. Immunol. 23, 1078. Lust, J.A., et al. 1992. Cytokine 4, 96. Sugita, T., et al. 1990. J. Exp. Med. 171, 2001. Yamasaki, K., et al. 1988. Science241, 825.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
07-May-2010 JSW
Synonyms
rhIL-6 sR
Description
Recombinant, human soluble interleukin-6 receptor expressed in S. frugiperda insect cells. Soluble form of the IL-6 receptor that binds IL-6 and mediates IL-6 signaling through interaction with gp 130. Elevated serum levels of soluble IL-6 receptors have been shown to be associated with a number of pathological states, including multiple myelomas, adult T cell leukemia, interstitial lung infection, and HIV infection.
Form
Lyophilized
Formulation
Lyophilized from sterile-filtered PBS, 50 µg BSA/µg IL-6 receptor.
Purity
≥97% by SDS-PAGE
Contaminants
Endotoxin: ≤1 EU/µg
Biological activity
ED₅₀= ≥5 ng/ml as measured by its ability to enhance IL-6-induced growth inhibition of mouse M1 myeloid leukemic cells
Solubility
Reconstitute to a concentration ≥100 µg/ml with sterile PBS containing at least 0.1% HSA or BSA.
Storage
≤ -70°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C. Avoid freeze/thaw cycles of solutions.
Toxicity
Standard Handling
References
Schobitz, B., et al. 1995. FASEB J. 9, 659. Yokoyama, A., et al. 1995. Clin. Exp. Immunol. 100, 325. Suzuki, H., et al. 1993. Eur. J. Immunol. 23, 1078. Lust, J.A., et al. 1992. Cytokine 4, 96. Sugita, T., et al. 1990. J. Exp. Med. 171, 2001. Yamasaki, K., et al. 1988. Science241, 825.
