Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

GF401 HumanKine® beta NGF, Human Recombinant Xeno-Free

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P01138
GF401
10 µg  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Special Offers

Bulk Size Quantities of HumanKine Growth Factors are Available.
Click Here for more information.

Key Spec Table

SourcePurity
HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE.
Description
Catalogue NumberGF401
Trade Name
  • HumanKine®
DescriptionHumanKine® beta NGF, Human Recombinant Xeno-Free
Alternate Names
  • Nerve Growth Factor
  • NGF
  • BNGF
  • Beta NGF
Background InformationNerve Growth Factor (β-NGF) is a well characterized neurotropic protein that plays a critical role in the development of sympathetic and some sensory neurons in the peripheral nervous system. In addition, NGF can also act in the central nervous system as a trophic factor for basal forebrain cholinergic neurons. NGF has also been shown to have biological effects on nonneuronal tissues. β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. The functional form of human β-NGF is a noncovalently disulfide-linked homodimer, of two 13.5 kDa polypeptide monomers (238 total amino acid residues).
References
Product Information
Formulation
PresentationProduct is presented in PBS and filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ300
Applications
Biological Information
PurityProduct is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE.
SourceHumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceThe specific activity was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line). ED50 is typically 1.5-8 ng/ml.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added.
Packaging Information
Material Size10 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
GF401 04053252905384

Documentation

HumanKine® beta NGF, Human Recombinant Xeno-Free SDS

Title

Safety Data Sheet (SDS) 

HumanKine® beta NGF, Human Recombinant Xeno-Free Certificates of Analysis

TitleLot Number
HumanKine#174; beta NGF, Human Recombinant Xeno-Free - QVP1303112 QVP1303112
HumanKine#174; beta NGF, Human Recombinant Xeno-Free - QVP1305282 QVP1305282
HumanKine® beta NGF, Human Recombinant Xeno-Free - VP1311190 VP1311190
HumanKine® beta NGF, -VP1504071 VP1504071
HumanKine® beta NGF, -VP1508058 VP1508058
HumanKine® beta NGF, Human Recombinant Xeno-Free - VP2201140 VP2201140
HumanKine® beta NGF, Human Recombinant Xeno-Free - VP2205121 VP2205121

Related Products & Applications

Product Families

Cytokines and Growth Factors

EMD Millipore offers a comprehensive range of highly purified bioactive cytokines and growth factors for use in human, mouse, and rat cell culture, stem cell differentiation and ELISA studies.
Learn More >>

Categories

Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors