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505823 Galectin-1 Antagonist, DB21 - Calbiochem

Overview

Replacement Information

Key Spec Table

Empirical Formula
C₈₃H₁₃₂N₁₈O₁₇

Products

Catalogue NumberPackaging Qty/Pack
5.05823.0001 Glass bottle 2 mg
Description
OverviewA dibenzofuran conjugated peptidomimetic (13-mer) that acts as an allosteric inhibitor of galectin-1 binding to cell surface glycans (IC50 = 3 µM). Shown to reduce the proliferation of endothelial cells and reduce vessel density in murine tumor models.
Catalogue Number505823
Brand Family Calbiochem®
SynonymsSVQNvaKL-[DBF]-IIVKLNA
References
ReferencesDings, R.P., et al, 2013, J. Pharm. Exp. Ther. 344, 589.
Product Information
FormWhite powder
Hill FormulaC₈₃H₁₃₂N₁₈O₁₇
Chemical formulaC₈₃H₁₃₂N₁₈O₁₇
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetGalectin-1
Primary Target IC<sub>50</sub>
Purity≥98% by HPLC
Physicochemical Information
Peptide SequenceSVQMKNva-[DBF]-IIVKLNA
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
5.05823.0001 04055977263077

Documentation

Galectin-1 Antagonist, DB21 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Dings, R.P., et al, 2013, J. Pharm. Exp. Ther. 344, 589.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision06-December-2013 JSW
SynonymsSVQNvaKL-[DBF]-IIVKLNA
DescriptionA dibenzofuran conjugated peptidomimetic (13-mer) that acts as an allosteric inhibitor of galectin-1 binding to cell surface glycans (IC50 = 3 µM). Shown to reduce the proliferation of endothelial cells and reduce vessel density in murine tumor models.
FormWhite powder
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₈₃H₁₃₂N₁₈O₁₇
Peptide SequenceSVQMKNva-[DBF]-IIVKLNA
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (10 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesDings, R.P., et al, 2013, J. Pharm. Exp. Ther. 344, 589.