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341501 FeTMPyP - Calbiochem

Overview

Key Spec Table

Empirical Formula
C₄₄H₃₆Cl₅FeN₈

Products

Catalogue NumberPackaging Qty/Pack
341501-10MGCN Plastic ampoule 10 mg
Description
OverviewCatalyzes the isomerization of peroxynitrite (ONOO) to nitrate (NO3) under physiological conditions and at realistic dose-derived concentrations (Kcat = 2.2 x 106 M-1s-1). Effectively prevents the oxidation of lipid components by peroxynitrite. Also catalytically decomposes superoxide radicals (O2·). Irradiation of the aqueous solution at 335 nm releases hydroxyl (OH·) radicals. FeTMPyP can also serve as a potential for drug detoxification of reactive oxygen species (ROS).
Catalogue Number341501
Brand Family Calbiochem®
Synonyms5,10,15,20-Tetrakis(N-methyl-4ʹ-pyridyl)porphinato Iron (III) Chloride, FeIIITMPyP(Cl)
References
ReferencesLee, J., et al. 1998. J. Am. Chem. Soc. 120, 7493.
Hunt, J.A., et al. 1997. Chem. Biol. 4, 845.
Marla, S.S., et al. 1997. Proc. Natl. Acad. Sci. USA 94, 14243.
Stern, M.K., et al. 1996. J. Am. Chem. Soc. 118, 8735.
Faraggi, M., et al. 1984. Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 46, 703.
Product Information
ATP CompetitiveN
FormBrown solid
Hill FormulaC₄₄H₃₆Cl₅FeN₈
Chemical formulaC₄₄H₃₆Cl₅FeN₈
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetPeroxynitrite (ONOO-)
Primary Target IC<sub>50</sub>Kcat = 2.2 x 106 M-1s-1 in catalyzing the isomerization of peroxynitrite (ONOO-) to nitrate (NO3-) under physiological conditions
Purity≥90% by TLC
Physicochemical Information
Cell permeableN
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
Global Trade Item Number
Catalogue Number GTIN
341501-10MGCN 04055977215014