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341273 Factor D, Human

Factor D, Human, is a native single-chain glycoprotein with serine protease activity. Cleaves, and thus activates, Factor B during activation of complement via the alternative pathway.

Factor D, Human MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: C3 Activator Convertase, Adipsin

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341273
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Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
341273-25UGCN Plastic ampoule 25 μg
Description
OverviewNative factor D from human serum. Single-chain glycoprotein composed of 222 amino acids, present in normal human serum at about 1.4 µg/ml. Serine protease that cleaves, and thus activates, Factor B during activation of complement via the alternative pathway. Has recently been shown to be identical to adipsin, a serine protease secreted into the bloodstream by adipocytes.
Catalogue Number341273
Brand Family Calbiochem®
SynonymsC3 Activator Convertase, Adipsin
References
ReferencesJing, H., et al. 1999. EMBO J. 18, 804.
Volankis, J.E., et al. 1985. N. Engl. J. Med. 312, 395.
Niemann, M.A., et al. 1984. J. Immunol. 132, 809.
Product Information
FormLiquid
FormulationIn PBS, pH 7.2.
Quality LevelMQ100
Applications
Biological Information
Biological activityIgG, IgA, IgM, Factor H, Factor B, or albumin: ≤trace amounts
Purity≥90% by SDS-PAGE
SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
341273-25UGCN 04055977215557

Documentation

Factor D, Human SDS

Title

Safety Data Sheet (SDS) 

Factor D, Human Certificates of Analysis

TitleLot Number
341273

References

Reference overview
Jing, H., et al. 1999. EMBO J. 18, 804.
Volankis, J.E., et al. 1985. N. Engl. J. Med. 312, 395.
Niemann, M.A., et al. 1984. J. Immunol. 132, 809.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision24-June-2008 RFH
SynonymsC3 Activator Convertase, Adipsin
DescriptionNative factor D from human serum. Single-chain glycoprotein composed of 222 amino acids present in normal human serum at about 1.4 µg/ml. Serine protease that cleaves, and thus activates, Factor B during activation of complement via the alternative pathway. Has recently been shown to be identical to adipsin, a serine protease secreted into the bloodstream by adipocytes.
FormLiquid
FormulationIn PBS, pH 7.2.
SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Purity≥90% by SDS-PAGE
Biological activityIgG, IgA, IgM, Factor H, Factor B, or albumin: ≤trace amounts
Storage Avoid freeze/thaw
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Toxicity Standard Handling
ReferencesJing, H., et al. 1999. EMBO J. 18, 804.
Volankis, J.E., et al. 1985. N. Engl. J. Med. 312, 395.
Niemann, M.A., et al. 1984. J. Immunol. 132, 809.