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204881 Complement C3a, Human

Complement C3a, Human, is a native, single chain C3a complement component. It has many biological activities, such as smooth muscle contraction, platelet activation, & immunoregulatory reactions.

Complement C3a, Human MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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204881
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Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
204881-50UGCN Plastic ampoule 50 μg
Description
OverviewNative, human C3a complement component. Single chain, 77 amino acid peptide. Activation of either complement pathway can result in formation of C3-cleaving enzymes (C3 convertases) on target surfaces. The C3 convertase enzymes of either complement activation pathway will cleave the C3 α-chain at peptide bond 77 resulting in the production and release of the C3a peptide. C3a, one of the three complement-derived anaphylatoxins, expresses a wide variety of biological activities which include smooth muscle contraction, platelet and neutrophil activation and aggregation, skin wheal and flare, and immunoregulatory reactions.
Catalogue Number204881
Brand Family Calbiochem®
References
ReferencesHugli, T.E. 1989. Curr. Top. Micro. Immunol. 153, 181.
Hugli, T.E. 1986. Complement 3, 111.
Product Information
FormLiquid
FormulationIn PBS, pH 7.2, sterile-filtered through a 0.22 µm filter.
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by SDS-PAGE
SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
ContaminantsC3adesArg; ≤10%
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
204881-50UGCN 04055977219746

Documentation

Complement C3a, Human SDS

Title

Safety Data Sheet (SDS) 

Complement C3a, Human Certificates of Analysis

TitleLot Number
204881

References

Reference overview
Hugli, T.E. 1989. Curr. Top. Micro. Immunol. 153, 181.
Hugli, T.E. 1986. Complement 3, 111.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-May-2008 RFH
DescriptionNative, human C3a complement component. Single chain, 77 amino acid peptide. Activation of either complement pathway can result in formation of C3-cleaving enzyme (C3 convertases) on target surfaces. The C3 convertase enzymes of either complement activation pathway will cleave the C3 α-chain at peptide bond 77, resulting in the production and release of the C3a peptide. C3a, one of the three complement-derived anaphylatoxins, expresses a wide variety of biological activities, which include smooth muscle contraction, platelet and neutrophil activation and aggregation, skin wheal and flare, and immunoregulatory reactions.
FormLiquid
FormulationIn PBS, pH 7.2, sterile-filtered through a 0.22 µm filter.
Concentration Label Please refer to vial label for lot-specific concentration
SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Purity≥95% by SDS-PAGE
ContaminantsC3adesArg; ≤10%
Storage Avoid freeze/thaw
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Toxicity Standard Handling
ReferencesHugli, T.E. 1989. Curr. Top. Micro. Immunol. 153, 181.
Hugli, T.E. 1986. Complement 3, 111.