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218753 Caspase-5 Inhibitor I

Overview

Key Spec Table

Empirical Formula
C₃₇H₄₂FN₇O₁₀

Products

Catalogue NumberPackaging Qty/Pack
218753-1MGCN Plastic ampoule 1 mg
Description
OverviewA potent, cell-permeable, and irreversible inhibitor of caspase-5. Strongly inhibits caspase-1. Also inhibits caspase-4 and caspase-8.
Catalogue Number218753
Brand Family Calbiochem®
SynonymsZ-WE(OMe)HD(OMe)-FMK
References
ReferencesGarcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Rano, T., et al. 1997. Chem. Biol. 4, 149.
Product Information
FormWhite solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₃₇H₄₂FN₇O₁₀
Chemical formulaC₃₇H₄₂FN₇O₁₀
ReversibleN
Quality LevelMQ100
Biological Information
Primary Targetcaspase-1, caspase-4, caspase-5, caspase-8
Puritysingle spot by TLC
Physicochemical Information
Cell permeableY
Peptide SequenceZ-Trp-Glu(OMe)-His-Asp(OMe)-CH₂F*
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
Global Trade Item Number
Catalogue Number GTIN
218753-1MGCN 04055977219098