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06-570-AF488 Anti-phospho Histone H3 (Ser10) Antibody, Alexa Fluor® 488 Conjugate

Anti-phospho-H3 (Ser10), Alexa Fluor® 488 Conjugate is a purified rabbit polyclonal that detects Histone H3 phosphorylated at serine 10. This Ab is labeled with Alexa Fluor 488 and validated in IC. The unconjugated version of this antibody is highly published and proven in ICC, IP & WB.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epitope Tags & General Use Research Sub-Category: Epitope Tags Gene Symbol: HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3F, H3FI, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, H3FF, HIST1H3J, H3FJ, HIST3H3, H3FT, H3T, MGC126886 UniProt Number: Q16695
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06-570-AF488
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MICCRbAlexaFluor®488Polyclonal Antibody
Description
Catalogue Number06-570-AF488
DescriptionAnti-phospho Histone H3 (Ser10) Antibody, Alexa Fluor® 488 Conjugate
Alternate Names
  • H3S10P
  • Histone H3 (phospho Ser10)
  • H3 histone, family 3A
  • H3.3A
  • H3 histone, family 3B
  • H3.3B
Background InformationHistone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
References
Product Information
FormatAlexaFluor®488
PresentationPurified rabbit conjugate in buffer containing PBS, 15 mg/ml BSA, and 0.1% Sodium Azide.
Quality LevelMQ100
Applications
ApplicationAnti-phospho-H3 (Ser10), Alexa Fluor® 488 Conjugate is a purified rabbit polyclonal that detects Histone H3 phosphorylated at serine 10. This Ab is labeled with Alexa Fluor 488 and validated in IC. The unconjugated version of this antibody is highly published and proven in ICC, IP & WB.
Key Applications
  • Immunocytochemistry
Application NotesImmunocytochemistry Analysis: A 1:50 dilution from a representative lot detected phospho Histone H3 (Ser10) in NIH/3T3 cells.

Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected Histone H3 (Ser10) in HeLa cell lysate.
Biological Information
ImmunogenLinear peptide corresponding to phospho-Histone H3 (Ser10).
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
  • Mouse
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • HIST1H3A
  • H3FA
  • HIST1H3B
  • H3FL
  • HIST1H3C
  • H3FC
  • HIST1H3D
  • H3FB
  • HIST1H3E
  • H3FD
  • HIST1H3F
  • H3FI
  • HIST1H3G
  • H3FH
  • HIST1H3H
  • H3FK
  • HIST1H3I
  • H3FF
  • HIST1H3J
  • H3FJ
  • HIST3H3
  • H3FT
  • H3T
  • MGC126886
Purification MethodProtein A Purfied
UniProt Number
Molecular Weight~17 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunocytochemistry in HeLa cells.

Immunocytochemistry Analysis: A 1:50 dilution of this antibody detected phospho Histone H3 (Ser10) in HeLa cells.

Alexa Fluor® is a registered trademark of Life Technologies®.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
06-570-AF488 04053252971914

Documentation

Anti-phospho Histone H3 (Ser10) Antibody, Alexa Fluor® 488 Conjugate SDS

Title

Safety Data Sheet (SDS) 

Anti-phospho Histone H3 (Ser10) Antibody, Alexa Fluor® 488 Conjugate Certificates of Analysis

TitleLot Number
Anti-phospho Histone H3 (Ser10), -2566795 2566795
Anti-phospho Histone H3 (Ser10), -2659578 2659578
Anti-phospho Histone H3 (Ser10), -2712582 2712582
Anti-phospho Histone H3 (Ser10), Alexa Fluor® 488 Conjugate 2955671
Anti-phospho Histone H3 (Ser10), Alexa Fluor® 488 Conjugate 2926480
Anti-phospho Histone H3 (Ser10), Alexa Fluor® 488 Conjugate 3089564
Anti-phospho Histone H3 (Ser10), Alexa Fluor® 488 Conjugate - Q2411267 Q2411267
Anti-phospho Histone H3 (Ser10), Alexa Fluor® 488 Conjugate - 3230531 3230531
Anti-phospho Histone H3 (Ser10), Alexa Fluor® 488 Conjugate - 3246199 3246199
Anti-phospho Histone H3 (Ser10), Alexa Fluor® 488 Conjugate - 3451443 3451443
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