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ABE1358 Anti-Zinc finger protein 593

Anti-Zinc finger protein 593 Antibody, Cat. No. ABE1358, is a highly specific rabbit polyclonal antibody that targets Zinc finger protein 593 and has been tested in Immunoprecipitation and Western Blotting.

Anti-Zinc finger protein 593 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Gene Symbol: ZNF593, ZT86 UniProt Number: O00488
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ABE1358
100 µL  
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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
MIP, WBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABE1358
DescriptionAnti-Zinc finger protein 593
Alternate Names
  • ZFP593
  • Zinc finger protein T86
Background InformationZinc finger protein 593 (UniProt: O00488; also known as Zinc finger protein T86) is encoded by the ZNF593 (also known as ZT86) gene (Gene ID: 51042) in human. Zinc fingers are small protein domains wherein zinc plays a structural role contributing to the stability of the domain. Proteins containing zinc fingers are structurally diverse and perform a broad range of functions, including DNA replication and repair, transcription and translation, metabolism, cell proliferation, and apoptosis. Zinc finger domain 593 (ZNF593) belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family and contains a single C2H2 type zinc finger (amino acids 61-85). ZFP593 is largely disordered, with the exception of the zinc finger domain. It displays ubiquitous distribution and has been detected in spleen, prostate, testis, small intestine, and colon and in lower levels in thymus and peripheral blood leukocytes. ZFP593 is shown to negatively modulate the DNA binding activity of Oct-2. It can act either by binding to DNA octamer or by interacting with Oct-2. (Ref.: Srikrishna, S., et al. (2003), Nucleic Acid Res. 31(2): 532-550).
References
Product Information
FormatAffinity Purified
PresentationPurified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-Zinc finger protein 593 Antibody, Cat. No. ABE1358, is a highly specific rabbit polyclonal antibody that targets Zinc finger protein 593 and has been tested in Immunoprecipitation and Western Blotting.
Key Applications
  • Immunoprecipitation
  • Western Blotting
Application NotesWestern Blotting Analysis: A 1:500 dilution from a representative lot detected Zinc finger protein 593 in mouse embryonic stem cells. (Courtesy of Dr Adrian Bracken from Trinity College, Dublin).

Immunoprecipitation Analysis: 2 ug from a representative lot detected Zinc finger protein 593 in mouse embryonic stem cells. (Courtesy of Dr Adrian Bracken from Trinity College, Dublin).
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to 14 amino acids from the C-terminal end of human Zinc finger protein 593.
ConcentrationPlease refer to lot specific datasheet.
HostRabbit
SpecificityThis polyclonal antibody detects zinc finger protein 593 in murine embryonic stem cells. It targets an epitope of 14 amino acids from the C-terminus.
Species Reactivity
  • Mouse
Species Reactivity NoteMouse. Predicted to react with Human, Bovine, Rhesus Macaque based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • ZNF593
  • ZT86
Purification MethodAffinity Purified
UniProt Number
Molecular Weight~15 kDa observed. 15.20 kDa calculated. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in mouse embryonic stem cells.

Western Blotting Analysis: A 1:500 dilution of this antibody detected Zinc finger protein 593 in 10 µg of mouse embryonic stem cells lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABE1358 04054839169588