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16-212 Anti-Myc Tag Antibody, clone 4A6, biotin conjugate

Detect Myc Tag using this Anti-Myc Tag Antibody, clone 4A6, biotin conjugate validated for use in WB.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epitope Tags & General Use Research Sub-Category: Epitope Tags Gene Symbol: MYC, C-MYC, c-Myc UniProt Number: P01106
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBMBiotinMonoclonal Antibody
Description
Catalogue Number16-212
Brand Family Upstate
Trade Name
  • Upstate
DescriptionAnti-Myc Tag Antibody, clone 4A6, biotin conjugate
OverviewImmunogen: peptide corresponding to amino acids 410-420 (MEQKLISEEDL) of human Myc

Specificity: Recognizes and is specific for recombinant proteins containing the Myc epitope tag (EQKLISEEDL) in a variety of sequence contexts. Also recognizes human Myc.

Species Cross-reactivity: Human, others not tested

Ig Type: IgG

Host: Mouse

Molecular Weight: Varies depending upon the protein which is tagged
References
Product Information
FormatBiotin
PresentationPBS and 0.05% sodium azide before the addition of glycerol to 30%
Quality LevelMQ100
Applications
ApplicationDetect Myc Tag using this Anti-Myc Tag Antibody, clone 4A6, biotin conjugate validated for use in WB.
Key Applications
  • Western Blotting
Biological Information
Cloneclone 4A6
HostMouse
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Gene Symbol
  • MYC
  • C-MYC
  • c-Myc
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P01106 # Participates in the regulation of gene transcription. Binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.
SIZE: 439 amino acids; 48804 Da
SUBUNIT: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX. Interacts with TAF1C and SPAG9. Interacts with PARP10. Interacts with JARID1A and JARID1B.
SUBCELLULAR LOCATION: Nucleus.
PTM: Phosphorylated by PRKDC.
DISEASE: SwissProt: P01106 # Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. & A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with BTG1.
SIMILARITY: SwissProt: P01106 ## Contains 1 basic helix-loop-helix (bHLH) domain.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assuranceroutinely evaluated by western blot on Myc-tagged recombinant protein
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions1 year at -20°C
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
16-212 04053252623035

Documentation

Anti-Myc Tag Antibody, clone 4A6, biotin conjugate SDS

Title

Safety Data Sheet (SDS) 

Anti-Myc Tag Antibody, clone 4A6, biotin conjugate Certificates of Analysis

TitleLot Number
Anti-Myc Tag, clone 4A6, biotin conjugate (mouse monoclonal IgG1) - 2361471 2361471
Anti-Myc Tag, clone 4A6, biotin conjugate (mouse monoclonal IgG1) - 2398910 2398910
Anti-Myc Tag, clone 4A6, biotin conjugate (mouse monoclonal IgG1) - DAM1408780 DAM1408780
Anti-Myc Tag, clone 4A6, biotin conjugate - 26847 26847
Anti-Myc Tag, clone 4A6, biotin conjugate - 3144495 3144495
Anti-Myc Tag, clone 4A6, biotin conjugate - 3485011 3485011
Anti-Myc Tag, clone 4A6, biotin conjugate - 3671808 3671808
Anti-Myc Tag, clone 4A6, biotin conjugate - 3677763 3677763
Anti-Myc Tag, clone 4A6, biotin conjugate - 3713397 3713397
Anti-Myc Tag, clone 4A6, biotin conjugate - 3792890 3792890
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Alternative Format

Catalogue Number Description
05-724 Anti-Myc Tag Antibody, clone 4A6
05-724MG Anti-Myc Tag Antibody, clone 4A6
16-213 Anti-Myc Tag Antibody, clone 4A6, HRP conjugate
16-219 Anti-Myc Tag Antibody, clone 4A6, agarose conjugate
16-224 Anti-Myc Tag Antibody, clone 4A6, Alexa Fluor® 488 conjugate
16-225 Anti-Myc Tag Antibody, clone 4A6, Alexa Fluor® 555 conjugate

Product Families

Myc Tag Antibodies

Millipore’s Anti-myc antibodies demonstrate specificity against the myc-tag. See below for related products for myc. All Millipore antibodies are based on the expertise of Upstate & Chemicon.
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Categories

Life Science Research > Antibodies and Assays > Primary Antibodies