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AB15708C3 Anti-Beta III Tubulin, Cy3 Conjugate Antibody

This Anti-Beta III Tubulin, Cy3 Conjugate Antibody is validated for use in ICC for the detection of Beta III Tubulin.

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Research Category: Neuroscience Research Sub-Category: Neuronal & Glial Markers, Neurofilament & Neuron Metabolism Gene Symbol: TUBB3, TUBB4, MC1R, beta-4 UniProt Number: Q13509
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AB15708C3
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, RICCRbCy3Polyclonal Antibody
Description
Catalogue NumberAB15708C3
DescriptionAnti-Beta III Tubulin, Cy3 Conjugate Antibody
Background InformationTubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. The most common members of the tubulin family are α-tubulin and β-tubulin. Tubulin dimers, typically composed of α- and β-tubulin subunits, assemble onto microtubules forming large polymers. β-III tubulin is a unique microtubule subunit that is found expressed almost exclusively in neurons. Due to the unique expression pattern of β-III tubulin it is often utilized as a marker to identify neuronal cells from other brain cells such as glia which do not express it. β-III tubulin also serves as a cytoarchitectural marker since it is primarily found within neurite extensions.
Product Information
FormatCy3
Control
  • Rat E18 cortex cells
PresentationPurified rabbit polyclonal conjugated to Cy3 in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Quality LevelMQ100
Applications
ApplicationThis Anti-Beta III Tubulin, Cy3 Conjugate Antibody is validated for use in ICC for the detection of Beta III Tubulin.
Key Applications
  • Immunocytochemistry
Biological Information
ImmunogenSynthetic linear peptide corresponding to human Beta III Tubulin.
HostRabbit
Species Reactivity
  • Human
  • Mouse
  • Rat
Species Reactivity NoteDemonstrated to react with Rat. Predicted to react with Human and Mouse based on 100% sequence homology.
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • TUBB3
  • TUBB4
  • MC1R
  • beta-4
Purification MethodAffinity Purfied
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q13509 # Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
SIZE: 450 amino acids; 50433 Da
SUBUNIT: Dimer of alpha and beta chains.
DOMAIN:SwissProt: Q13509 The highly acidic C-terminal region may bind cations such as calcium.
SIMILARITY: Belongs to the tubulin family.
Molecular Weight50 kDa calculated
Product Usage Statements
Quality AssuranceEvaluated by Immunocytochemistry in rat E18 cortex cells.
Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Beta III Tubulin in rat E18 cortex cells.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µL
Global Trade Item Number
Catalogue Number GTIN
AB15708C3 04053252537189