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454202 8-Methoxymethyl-3-isobutyl-1-methylxanthine - CAS 78033-08-6 - Calbiochem

A cell-permeable selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE I; IC₅₀ = 4 µM).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 8-Methoxymethyl-IBMX

Primary Target: PDE 1
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
78033-08-6C₁₂H₁₈N₄O₃

Products

Catalogue NumberPackaging Qty/Pack
454202-10MGCN Plastic ampoule 10 mg
Description
OverviewA cell-permeable selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE I; IC50 = 4 µM).
Catalogue Number454202
Brand Family Calbiochem®
Synonyms8-Methoxymethyl-IBMX
References
ReferencesJackson, E.K., et al. 1997. J. Cardiovasc. Pharmacol. 30, 798.
Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331.
Han, P., et al. 1989. J. Biol. Chem. 274, 22337.
Product Information
CAS number78033-08-6
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₂H₁₈N₄O₃
Chemical formulaC₁₂H₁₈N₄O₃
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetPDE 1
Primary Target IC<sub>50</sub>4 µM against Ca2+-calmodulin-dependent phosphodiesterase (PDE I)
Purity≥98% by TLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
454202-10MGCN 04055977204742

Documentation

8-Methoxymethyl-3-isobutyl-1-methylxanthine - CAS 78033-08-6 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

8-Methoxymethyl-3-isobutyl-1-methylxanthine - CAS 78033-08-6 - Calbiochem Certificates of Analysis

TitleLot Number
454202

References

Reference overview
Jackson, E.K., et al. 1997. J. Cardiovasc. Pharmacol. 30, 798.
Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331.
Han, P., et al. 1989. J. Biol. Chem. 274, 22337.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-August-2008 RFH
Synonyms8-Methoxymethyl-IBMX
DescriptionA cell-permeable, selective inhibitor of Ca2+-calmodulin-dependent phosphodiesterase (PDE I, IC50 = 4 µM).
FormWhite solid
CAS number78033-08-6
Chemical formulaC₁₂H₁₈N₄O₃
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityDMSO (5 mg/ml) or Ethanol (2 mg/ml)
Storage +15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesJackson, E.K., et al. 1997. J. Cardiovasc. Pharmacol. 30, 798.
Ahn, H.S., et al. 1989. Biochem. Pharmacol. 38, 3331.
Han, P., et al. 1989. J. Biol. Chem. 274, 22337.